Burden of gastroesophageal reflux disease in Shanghai, China

Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver
R WangJ He

Abstract

Data on the impact of gastroesophageal reflux disease (GERD) on health-related quality of life (HRQL) in Asian countries are scarce. This study evaluated the impact of GERD on HRQL in Shanghai, China. One thousand two hundred adult inhabitants of Shanghai, selected using randomized cluster sampling. Participants completed Mandarin versions of the Reflux Disease Questionnaire (RDQ), GERD impact scale, quality of life in reflux and dyspepsia (QOLRAD) questionnaire and short-form-36 (SF-36). GERD was defined as heartburn and/or regurgitation of any frequency during the 1-week recall period of the RDQ. A clinically meaningful impairment of HRQL was defined as a statistically significant decrease of >or=0.5 points in a QOLRAD dimension or >or=5 points in an SF-36 dimension. Overall, 1034 subjects completed the survey (86.2% response rate); 919 responses were suitable for analysis. The prevalence of GERD was 6.2%. GERD was associated with meaningfully impaired HRQL in the QOLRAD dimensions of vitality, eating/drinking and emotional well-being, but not sleep or physical/social functioning, and in all SF-36 dimensions except social functioning. Respondents with GERD experienced eating and drinking problems (47%), sleep impairment (32%)...Continue Reading

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Citations

Sep 25, 2012·Digestive Diseases and Sciences·Eun Mi SongJi Min Jung
Jan 14, 2011·Journal of Gastroenterology and Hepatology·Khean-Lee Goh
Jun 11, 2010·Journal of Neurogastroenterology and Motility·Hye-Kyung JungNicholas J Talley
Mar 4, 2011·Journal of Neurogastroenterology and Motility·Hye-Kyung Jung
Dec 23, 2014·Gastroenterology Research and Practice·Huihui SunShuchang Xu
Dec 4, 2010·Best Practice & Research. Clinical Gastroenterology·Sabine Roman, John E Pandolfino
May 17, 2018·Annals of the New York Academy of Sciences·Junichi AkiyamaGeorge Triadafilopoulos
Sep 13, 2017·Middle East Journal of Digestive Diseases·Zohre KhodamoradiReza Malekzadeh
Jul 23, 2021·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Gui ChenXiaowen Zhang

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