Burden of Illness in Type 2 Diabetes Mellitus

Journal of Managed Care & Specialty Pharmacy
Anthony CannonMichael Shannon

Abstract

An estimated 30.2 million Americans have diabetes, and this number is expected to increase based on trends over recent decades and compounded by an aging U.S. As reviewed in this article, type 2 diabetes mellitus (T2DM) is associated with impaired health-related quality of life (HRQoL) and with a substantial socioeconomic burden. Compared with individuals without T2DM, those with T2DM have worse HRQoL, greater decrements in HRQoL over time, and possibly greater depressive symptomology. Diabetes-related complications and comorbidities (e.g., obesity and cardiovascular disease) are associated with worse HRQoL. Hypoglycemic episodes are associated with reduced HRQoL and greater levels of depression; they can also interfere with social and occupational activities. In turn, low HRQoL can be a driver for poor glycemic control. In 2012, the total estimated cost associated with diagnosed diabetes in the United States was $245 billion. Factors contributing to increased health care resource utilization and costs in patients with T2DM include medical comorbidities, diabetes-related complications, inadequate glycemic control, and hypoglycemic episodes. Readmission is a key driver of hospital-related costs and is more common among elderly p...Continue Reading

References

Aug 10, 1999·Diabetes/metabolism Research and Reviews·R R Rubin, M Peyrot
Mar 20, 2003·Current Diabetes Reports·William H Polonsky
Sep 3, 2005·Journal of Managed Care Pharmacy : JMCP·Sharashchandra ShettyAlan K Oglesby
Sep 24, 2005·Diabetic Medicine : a Journal of the British Diabetic Association·M PeyrotS E Skovlund
Feb 9, 2006·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·F A Luscombe
Aug 21, 2010·Health and Quality of Life Outcomes·Fernando Alvarez-GuisasolaPanagiotis Mavros
Jan 5, 2011·Diabetes Care·Jeffrey S GonzalezWilliam H Polonsky
Jun 11, 2011·The American Journal of Geriatric Pharmacotherapy·Sharon B DybiczBruce Stuart
Feb 3, 2012·Diabetes Research and Clinical Practice·Andrew J GreenUNKNOWN SHIELD Study Group
Mar 8, 2013·Diabetes Care·UNKNOWN American Diabetes Association
Mar 26, 2013·Diabetes Research and Clinical Practice·Leonor Guariguata
Aug 21, 2013·American Journal of Preventive Medicine·Xiaohui ZhuoThomas J Hoerger
Oct 8, 2013·Diabetes Therapy : Research, Treatment and Education of Diabetes and Related Disorders·Etie Moghissi
Feb 20, 2014·International Journal of Clinical Practice·J P H Wilding
Mar 1, 2014·Archives of public health = Archives belges de santé publique·Juliana L MeyersSean D Candrilli
Apr 4, 2014·North American Journal of Medical Sciences·Vishakha JainOmprakash Gupta
May 29, 2014·Population Health Management·Mary E CostantinoJonathan R Bouchard
Jul 31, 2014·Diabetes, Obesity & Metabolism·W M Valencia, H Florez
Jan 22, 2015·Population Health Management·Amit D RavalUsha Sambamoorthi
Mar 3, 2015·Journal of Managed Care & Specialty Pharmacy·Sumesh KachrooVivian Fonseca
Jul 21, 2015·Journal of Medical Economics·Stephen S JohnstonIftekhar Kalsekar
Sep 5, 2015·Journal of Diabetes and Its Complications·W H PolonskyS V Edelman
Jan 6, 2016·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·Alan J GarberUNKNOWN American College of Endocrinology (ACE)
Jan 23, 2016·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·Alison HayesPhilip Clarke
Apr 29, 2016·Population Health Management·William R RowleyShannon Krohe
Jun 17, 2016·BMJ : British Medical Journal·Elbert S Huang
Aug 2, 2016·Annals of Internal Medicine·Daniel MurphyUNKNOWN Centers for Disease Control and Prevention Chronic Kidney Disease Surveillance Team

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Citations

Feb 12, 2020·Journal of Clinical Laboratory Analysis·Tomáš ŠálekPetr Ponížil
Nov 7, 2019·Journal of Evaluation in Clinical Practice·Tzu-Ho TsaiYiing-Jenq Chou
Sep 8, 2020·The Journal of Clinical Endocrinology and Metabolism·Peng-Fei Li, Wei-Liang Chen
Sep 11, 2020·Journal of Clinical Pharmacy and Therapeutics·Jennifer Trujillo
Jan 18, 2020·BioMed Research International·Periyanaina KesikaChaiyavat Chaiyasut
Jul 14, 2020·Journal of Diabetes Research·Jiarong LvShizhong Bu
May 6, 2020·Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Métabolisme·Mengwei LiuWanyang Liu
Oct 6, 2020·Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG·Juliane WeilandtWiebke K Peitsch
Jan 7, 2021·Journal of Human Nutrition and Dietetics : the Official Journal of the British Dietetic Association·Natalya LukomskyjAnna Rangan
Jan 21, 2021·Clinical Interventions in Aging·Jie WangXiaokun Li
Apr 11, 2021·Journal of Diabetes and Its Complications·Lizheng ShiBelinda Childs
May 1, 2021·International Journal of Environmental Research and Public Health·Jun-Hui WuYong-Hua Hu
May 28, 2021·Diabetes Therapy : Research, Treatment and Education of Diabetes and Related Disorders·Heather GelhornKristina S Boye

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