Burden of illness of multiple sclerosis: Part I: Cost of illness. The Canadian Burden of Illness Study Group

The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques

Abstract

Multiple sclerosis (MS) is a common neurologic disease in young and middle-aged adults affecting approximately 35,000 Canadians. The objectives of this study were to estimate the annual and lifetime costs of MS from the Canadian societal perspective. Patients were consecutively recruited by neurologists in 14 MS outpatient clinics across Canada. They were classified according to the Expanded Disability Status Scale (EDSS) into three groups: mild (EDSS < or = 2.5), moderate (EDSS = 3.0-6.0) and severe (EDSS > or = 6.5). Sociodemographic, clinical and resource utilization data were collected retrospectively for the three months prior to patient inclusion. Costing of resources was performed from Ministry of Health, private third party payers, patient and societal perspectives. Average Canadian costs ($CDN 1995) were valued from available provincial data. A total of 198 patients were included in the analysis (mild: n = 62, moderate: n = 68 and severe: n = 68). Costs increased with increasing EDSS scores, from all perspectives. The annualized societal costs per patient were $CDN14,523, $CDN21,698 and $CDN37,024 for the mild, moderate and severe groups, respectively. In all severity groups, most of the financial burden is borne by pa...Continue Reading

References

Jan 1, 1992·International Journal of Rehabilitation Research. Internationale Zeitschrift Für Rehabilitationsforschung. Revue Internationale De Recherches De Réadaptation·M Catanzaro, C Weinert
May 1, 1992·Neurology·A D SadovnickD W Paty
Jan 1, 1986·International Journal of Rehabilitation Research. Internationale Zeitschrift Für Rehabilitationsforschung. Revue Internationale De Recherches De Réadaptation·A B KornblithH M Baum
Oct 1, 1981·The Journal of the Society of Occupational Medicine·J N Mitchell
Mar 1, 1983·Annals of Neurology·C M PoserW W Tourtellotte
Aug 1, 1994·International Journal of Epidemiology·R E DalesR Burnett
Sep 15, 1995·American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists·C C BeckerJ O Fleming
Jan 1, 1996·Disease-a-month : DM·S G Lynch, J W Rose
Dec 10, 1991·PharmacoEconomics·D A Freund, R S Dittus
Oct 4, 1996·PharmacoEconomics·M A Koopmanschap, F F Rutten
Mar 31, 1965·Annals of the New York Academy of Sciences·H J BAUERW WINKLER

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Citations

Sep 1, 1999·Multiple Sclerosis : Clinical and Laboratory Research·J S FischerD Paty
Oct 12, 1999·Multiple Sclerosis : Clinical and Laboratory Research·M W NortvedtB R Hanestad
Sep 11, 2001·Multiple Sclerosis : Clinical and Laboratory Research·M W NortvedtH I Nyland
Nov 29, 2001·Multiple Sclerosis : Clinical and Laboratory Research·M P AmatoL Rossi
May 31, 2003·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·K D BuscheL M Metz
Oct 1, 2005·Multiple Sclerosis : Clinical and Laboratory Research·Michael IskedjianAdel Gehshan
Sep 27, 2007·Multiple Sclerosis : Clinical and Laboratory Research·K V L TurpinW J Hader
Oct 9, 2008·BMC Health Services Research·Asmahan F AlshubailiAsser A Mabrouk
Sep 10, 2009·Multiple Sclerosis : Clinical and Laboratory Research·J M WessonJ Barber
May 30, 2009·Disability and Rehabilitation·Terry A DilorenzoMary Ann Picone
Apr 1, 2006·Expert Review of Pharmacoeconomics & Outcomes Research·Ewa Orlewska
Oct 19, 2010·Expert Review of Pharmacoeconomics & Outcomes Research·Joshua T Cohen
Dec 3, 2013·The European Journal of Health Economics : HEPAC : Health Economics in Prevention and Care·Uwe K ZettlPeter Flachenecker
Jun 26, 2001·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·L S WilsonS Ezzat
Dec 11, 2003·Multiple Sclerosis : Clinical and Laboratory Research·Ruth Ann MarrieJeffrey A Cohen
Mar 6, 2003·Multiple Sclerosis : Clinical and Laboratory Research·M W Nortvedt, T Riise
Dec 23, 2004·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·E OrlewskaA Czlonkowska
Feb 10, 2006·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Ariel Miller, Sara Dishon
Mar 30, 2005·Multiple Sclerosis : Clinical and Laboratory Research·M B PatwardhanT T Li
Nov 8, 2006·Multiple Sclerosis : Clinical and Laboratory Research·K GottbergL Widén Holmqvist
Apr 19, 2007·Multiple Sclerosis : Clinical and Laboratory Research·A G BeiskeUNKNOWN Nordic SPMS study group
Jun 30, 2007·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·Wilma M HopmanDonald G Brunet
May 29, 2008·Multiple Sclerosis : Clinical and Laboratory Research·J DrulovicM Manigoda
Feb 20, 2010·Multiple Sclerosis : Clinical and Laboratory Research·R A BermelR A Rudick
Aug 25, 2010·Drugs·Jessica SharacRamon Sabes-Figuera
Apr 25, 2000·Multiple Sclerosis : Clinical and Laboratory Research·D T GrimaL Lafortune
May 20, 2004·British Journal of Nursing : BJN·Sue Woodward
Feb 6, 2004·Multiple Sclerosis : Clinical and Laboratory Research·J M Morales-GonzálesUNKNOWN GEDMA Study Group
Dec 4, 2004·Journal of Health Psychology·Marita P McCabew, Margaret De Judicibus
Aug 21, 2003·Multiple Sclerosis : Clinical and Laboratory Research·A C J W JanssensR Q Hintzen
Jan 30, 2007·Current Medical Research and Opinion·Michael IskedjianThomas R Einarson
May 22, 2007·International Journal of Behavioral Medicine·Margaret A De Judicibus, Marita P McCabe
Jul 7, 2007·Multiple Sclerosis : Clinical and Laboratory Research·F PattiUNKNOWN Italian Study Group On Quality Of Life In Ms
Apr 21, 2010·PharmacoEconomics·Huseyin NaciAmy Duhig
Nov 23, 2010·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·J-B ChansonJ de Seze
May 17, 2014·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Daniel LubelskiThomas E Mroz

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