Burden of Implanted-Device-Detected Atrial High-Rate Episode Is Associated With Future Heart Failure Events - Clinical Significance of Asymptomatic Atrial Fibrillation in Patients With Implantable Cardiac Electronic Devices

Circulation Journal : Official Journal of the Japanese Circulation Society
Ryo NishinaritaJunya Ako

Abstract

The relationship between atrial high-rate episode (AHRE) burden (i.e., the frequency of atrial tachyarrhythmia) and heart failure (HF) risk is unclear. We hypothesized that new-onset and higher burden of AHRE are associated with HF. Methods and Results: We included 104 consecutive patients with cardiac implantable electronic devices (CIEDs) capable of continuous atrial rhythm monitoring. Patients with AF history were excluded. To stratify patients, AHREs were evaluated only during the initial 1 year after CIED implantation. The primary endpoint was all-cause death or new-onset or worsening HF that required unplanned hospitalization or readjustment of HF drug therapy. At 1 year after CIED implantation, 34/104 patients (33%) exhibited AHREs. No difference in basal clinical characteristics except for left ventricular ejection fraction between patients with and without new-onset AHREs was found. AHRE groups had more HF events than the non-AHRE group. All patients were divided into 3 groups based on AHRE burden: none, low, and high. Worsening HF was observed in 12 patients (12%). Cox hazard analysis revealed that AHRE and higher AHRE burden were independent predictive factors for worsening HF. The high group showed a higher risk for...Continue Reading

References

May 9, 2001·Pacing and Clinical Electrophysiology : PACE·W M PollakR D Mitrani
Jun 5, 2003·The American Journal of Cardiology·Jeff S Healey, Stuart J Connolly
Jan 13, 2004·Journal of the American College of Cardiology·Carsten W IsraelStefan H Hohnloser
Jul 1, 2005·Circulation Journal : Official Journal of the Japanese Circulation Society·Toshimi KoitabashiTohru Izumi
Nov 4, 2006·Journal of Cardiovascular Electrophysiology·Jim W CheungSuneet Mittal
Mar 6, 2007·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Thomas H Everett, Jeffrey E Olgin
Mar 21, 2007·Pacing and Clinical Electrophysiology : PACE·Michael V OrlovUNKNOWN Atrial High Rate Trial Investigators
Oct 22, 2009·Circulation. Arrhythmia and Electrophysiology·Taya V GlotzerPaul D Ziegler
Jan 13, 2012·The New England Journal of Medicine·Jeff S HealeyUNKNOWN ASSERT Investigators
Feb 28, 2013·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Andrea MazzaGiampiero Giordano
Feb 11, 2014·The American Journal of Cardiology·Sophie TaillandierLaurent Fauchier
Mar 3, 2017·Circulation Journal : Official Journal of the Japanese Circulation Society·Yutaka OginoKazuo Kimura
Mar 9, 2017·Clinical Cardiology·Polychronis E Dilaveris, Harold L Kennedy
Mar 23, 2017·European Heart Journal·Isabelle C Van GelderStuart J Connolly
Nov 24, 2018·AJNR. American Journal of Neuroradiology·E GhioneR Zivadinov

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Citations

Jun 4, 2021·Circulation Journal : Official Journal of the Japanese Circulation Society·Hidehira Fukaya
Jun 6, 2021·Cardiovascular Drugs and Therapy·Ioannis DoundoulakisKonstantinos Tsioufis
Nov 26, 2021·Circulation Journal : Official Journal of the Japanese Circulation Society·Hisashi Ogawa, Masaharu Akao

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