Burden of pneumococcal disease among adults in Southern Europe (Spain, Portugal, Italy, and Greece): a systematic review and meta-analysis.

Human Vaccines & Immunotherapeutics
Adoración Navarro-TornéCristina Méndez

Abstract

The aim was to summarize pneumococcal disease burden data among adults in Southern Europe and the potential impact of vaccines on epidemiology. Of 4779 identified studies, 272 were selected. Invasive pneumococcal disease (IPD) incidence was 15.08 (95% CI 11.01-20.65) in Spain versus 2.56 (95% CI 1.54-4.24) per 100,000 population in Italy. Pneumococcal pneumonia incidence was 19.59 (95% CI 10.74-35.74) in Spain versus 2.19 (95% CI 1.36-3.54) per 100,000 population in Italy. Analysis of IPD incidence in Spain comparing pre-and post- PCV7 and PCV13 periods unveiled a declining trend in vaccine-type IPD incidence (larger and statistically significant for the elderly), suggesting indirect effects of childhood vaccination programme. Data from Portugal, Greece and, to a lesser extent, Italy were sparse, thus improved surveillance is needed. Pneumococcal vaccination uptake, particularly among the elderly and adults with chronic and immunosuppressing conditions, should be improved, including shift to a higher-valency pneumococcal conjugate vaccine when available.

References

Mar 1, 1990·The Journal of International Medical Research·G Straneo, G Scarpazza
Jul 1, 1996·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·A BoschiniG Rezza
Dec 1, 1995·The Journal of Antimicrobial Chemotherapy·J GómezM Valdés
Jul 1, 1996·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·J GómezM Valdés
Oct 1, 1996·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·J RelloB Alvarez
Nov 1, 1996·American Journal of Respiratory and Critical Care Medicine·A TorresJ Serra
Jan 1, 1996·Respiration; International Review of Thoracic Diseases·R CosentiniL Allegra
Apr 1, 1997·Respiratory Medicine·A CazzadoriE Concia
Apr 1, 1997·European Journal of Epidemiology·S SalmasoS Squarcione
Aug 1, 1997·Journal of Chemotherapy·F GinesuA G Fois
Aug 26, 1998·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·J M CisnerosA Echaniz
Feb 13, 1999·Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease·R PallaresF Gudiol
Sep 3, 1999·American Journal of Respiratory and Critical Care Medicine·M RuizJ A Martinez
Apr 26, 2000·The European Respiratory Journal·J AlmirallX Balanzó
Jun 20, 2001·Medicina clínica·M JavaloyasF Gudiol
Aug 30, 2001·Archives of Internal Medicine·M FalgueraM Rubio-Caballero
Aug 16, 2001·Lancet·R PallaresJ Liñares
Sep 20, 2001·Medicina clínica·M Vaqueiro SubiratsF Segura Porta
Jun 5, 2002·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Ma L Pedro-BotetM Sabrià
Aug 6, 2002·Scandinavian Journal of Infectious Diseases·M JavaloyasF Gudiol
Dec 4, 2002·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·A FaustiniC A Perucci
Mar 1, 2003·The European Respiratory Journal·R ZalacainUNKNOWN Pneumonia in the elderly working group, Area de Tuberculosis e Infecciones Respiratorias
Apr 30, 2003·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Manuel L Fernández GuerreroMiguel de Górgolas
Sep 11, 2003·Clinical and Diagnostic Laboratory Immunology·Silvia Fernández-SerranoFrederic Manresa
Feb 26, 2004·Journal of Medical Virology·C López-PalomoJ A Girón-González
May 25, 2004·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Queralt JordanoAlbert Pahissa
Aug 4, 2004·Scandinavian Journal of Infectious Diseases·Nieves SopenaMarian García-Nuñez
Sep 24, 2004·Revista española de salud pública·Ana María Comes CastellanoMiguel Sanz Valero
Jan 18, 2005·Chest·Nieves SopenaUNKNOWN Neunos 2000 Study Group
Mar 9, 2005·Vaccine·Fortunato D'AnconaUNKNOWN Italian PNC-Euro working group
Apr 7, 2005·Revista clínica española·F Cobo Martínez, P Manchado Mañas
Jun 3, 2005·AIDS Research and Human Retroviruses·R RanieriA E Pontiroli
Jul 9, 2005·Anales de medicina interna : organo oficial de la Sociedad Española de Medicina Interna·A I Franco MorenoA M Martínez de la Casa Muñoz
Sep 13, 2005·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·F GutiérrezA M Hidalgo
Oct 12, 2005·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·E BouzaUNKNOWN Spanish Pneumococcal Infection Study Network (G03/103)
Apr 6, 2006·The European Respiratory Journal·A de RouxA Torres

❮ Previous
Next ❯

Software Mentioned

OpenDOAR
metaprop
Open
R

Related Concepts

Related Papers

Current Opinion in Infectious Diseases
Catia CillónizA Torres
Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
Amelieke J. H. CremersM. I. de Jonge
Annals of the American Thoracic Society
Andrew C BericalJennifer D Possick
© 2021 Meta ULC. All rights reserved