Burden of rotavirus gastroenteritis in children <5 years of age in Greece: hospital-based prospective surveillance (2008-2010)

BMJ Open
Andreas KonstantopoulosKatsiaryna Holl

Abstract

This study describes the epidemiology of rotavirus (RV) gastroenteritis (GE) disease following the introduction of RV vaccination in Greece in 2006. A prospective hospital-based surveillance. A multicentre study was conducted at six hospitals in Greece between July 2008 and March 2010. The hospitals selected served 70% of the paediatric population in Greece. Children aged <5 years who visited the emergency rooms (ERs) or hospitalised with acute GE or acquired acute GE 48 h after hospitalisation and with a confirmed RV-positive stool test were enrolled. The occurrence of RVGE among all acute GE ER visits and hospitalisations and the occurrence of nosocomial RVGE are reported with 95% exact CI. Age-specific proportions of RVGE, seasonality and prevalence of RV genotypes were estimated. Incidence rates of nosocomial acute GE and RVGE are expressed in terms of 1000 children-years with 95% exact Poisson CI. Median duration of hospitalisation and prolongation of hospitalisation due to nosocomial RVGE were reported. RVGE proportions were 10.7% (95% CI 5.5% to 18.3%) and 23.8% (95% CI 20.0% to 28.0%) of acute GE ER visits and hospitalisations, respectively; and 21.6% (95% CI 9.8% to 38.2%) of nosocomial acute GE cases. The majority of ...Continue Reading

Citations

Feb 16, 2016·The Journal of Hospital Infection·D HungerfordN Cunliffe
Mar 23, 2015·Diagnostic Microbiology and Infectious Disease·Kenneth H RandStephanie M Karst
May 18, 2016·Human Vaccines & Immunotherapeutics·G GervasiE Franco
Sep 12, 2017·Journal of Medical Virology·Riza DurmazUNKNOWN Turkish Rotavirus Surveillance Network

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