Abstract
Injecting drug users (IDUs) are the major risk group for HIV-1 infection in the China-Myanmar border area. There are a large number of Burmese IDUs living in Yunnan (Yunnan-mIDUs) who might be associated with the cross-border transmission of HIV-1. From 2010 to 2013, 617 Yunnan-mIDUs were recruited from three counties of Yunnan, 19.0% of whom were detected to be HIV-1 positive by serological testing. Partial HIV-1 p17, pol, vif-env, and env genes were amplified from the positive samples and were sequenced. Phylogenetic and HIV-1 subtyping analyses revealed that HIV-1 recombinant forms (RFs), including RF_BC (36.4%), RF_01BC (26.1%), RF_01C (9.1%) and RF_01B (1.1%), were predominant among this cohort. Of the identified HIV-1 strains, 14.8%, 9.1% and 3.4% belonged to subtype C, CRF01_AE and subtype B, respectively. Transmission cluster analysis showed that sequences from the Yunnan-mIDUs formed transmission clusters not only with those from Burmese IDUs but also with those from Chinese IDUs, indicating that Yunnan-mIDUs might acquire HIV-1 infection from or spread HIV-1 to both Burmese and Chinese IDUs. Phylogeographic analyses revealed three cross-border transmission patterns associated with Yunnan-mIDUs, in which Yunnan-mIDUs s...Continue Reading
References
Mar 4, 2000·Journal of Medical Ethics·D GuenterR Macklin
Mar 14, 2000·AIDS·C BeyrerX F Yu
Jul 20, 2002·AIDS·Rongge YangYutaka Takebe
Dec 16, 2005·Cell Research·Na He, Roger Detels
Feb 27, 2007·Lancet·Zunyou WuRoger Detels
Jul 4, 2008·Journal of Virology·Kok Keng TeeYutaka Takebe
Jun 1, 2010·Vaccine·Yutaka TakebeKok Keng Tee
Oct 28, 2010·AIDS Research and Human Retroviruses·Sanjay R MehtaDavey M Smith
Feb 2, 2011·PloS One·Yan-Heng ZhouYong-Tang Zheng
Apr 22, 2011·BMC Public Health·Lei ZhangDavid P Wilson
Aug 23, 2011·PloS One·Jun Liu, Chiyu Zhang
Feb 16, 2012·AIDS·Wei PangYong-Tang Zheng
Aug 25, 2012·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Jun LiuChiyu Zhang
Apr 5, 2013·Retrovirology·Dineke FrentzUNKNOWN SPREAD Programme
Jun 7, 2013·PloS One·Xiaoxu HanHong Shang
Nov 7, 2013·BMC Bioinformatics·Manon Ragonnet-CroninUNKNOWN UK HIV Drug Resistance Database
Mar 19, 2014·Drug and Alcohol Dependence·Lei LiJianhua Li
Aug 28, 2014·BMC Infectious Diseases·Yan-Heng ZhouYong-Tang Zheng
Sep 10, 2014·PloS One·Lei LiJianhua Li
Apr 18, 2015·BMC Public Health·Binghui WangXueshan Xia
May 15, 2015·AIDS Research and Human Retroviruses·Yan-Heng ZhouYong-Tang Zheng
Dec 3, 2015·EBioMedicine·Sanjay R MehtaDavey M Smith
Jul 10, 2016·AIDS Research and Human Retroviruses·Xin ChenYong-Tang Zheng
Aug 10, 2016·Infectious Diseases of Poverty·Xin ChenYong-Tang Zheng
Aug 31, 2016·Virulence·Xin ChenYong-Tang Zheng
Sep 23, 2016·PloS One·Zhenzhou WanChiyu Zhang
Oct 21, 2016·AIDS Research and Human Retroviruses·Yihong HuChiyu Zhang
Nov 9, 2016·AIDS Research and Human Retroviruses·Rebecca RoseOliver Laeyendecker
Feb 16, 2017·Journal of Medical Virology·Li ZhangXueshan Xia
Dec 21, 2017·AIDS Research and Human Retroviruses·Jing MiaoXueshan Xia
Jun 23, 2018·Virologica Sinica·Xin ChenYong-Tang Zheng
Citations
May 17, 2019·PloS One·Min ChenZhizhong Song
Nov 2, 2019·BMC Infectious Diseases·Li JiangHong Li
Dec 13, 2019·Journal of Neuroimmune Pharmacology : the Official Journal of the Society on NeuroImmune Pharmacology·Xu WangWen-Zhe Ho
Jan 10, 2020·AIDS Research and Human Retroviruses·Xuemei DengXingqi Dong
Aug 18, 2020·AIDS Research and Human Retroviruses·Ying-Na XieXin Chen
Nov 13, 2019·BMC Public Health·Min ChenZhizhong Song
Apr 2, 2020·Virologica Sinica·Xin ChenYong-Tang Zheng
May 6, 2020·Infection and Drug Resistance·Mei YeYong-Tang Zheng
Jul 31, 2019·BMC Infectious Diseases·Min ChenManhong Jia
May 7, 2019·Frontiers in Microbiology·Mei YeYong-Tang Zheng
Dec 9, 2020·AIDS Research and Human Retroviruses·Ying-Na XieHong Li
May 20, 2021·The Journal of Infection·Qinghua GaoXueshan Xia