PMID: 20653194Jul 27, 2010Paper

Burow's solution treatment for external auditory canal and mastoid cavity cholesteatoma

Nihon Jibiinkoka Gakkai kaiho
Yoshihiko TerayamaMasami Ohashi

Abstract

Burow's solution, 13% aluminum acetate dissolved in water developed as ear drops by German Dr. Karl August Burow in the mid-1800s, was confirmed by Mahoney (1980) and Thorp et al. (2000) to act on chronic suppurative otitis media without ototoxicity. We have found it satisfactory in treating otitis media and other intractable inflammation and fungal infection of the external auditory canal. We report its potent effect in 2 cases of external auditory canal cholesteatoma (EACC) and 1 of mastoid cavity cholesteatoma (MCC)-the first such report insofar as we knew. Case 1 of EACC involved an 8-year-old boy with cholesteatoma debris in a bony groove evidencing defective skin just posteroinferior to the left tympanic membrane. EACC was cured after a single Burow's solution instillation. Case 2 of EACC was a 31-year-old woman whose left ear canal was filled by a keratin mass with pus positive for methicillin-resistant staphylococcus aureus (MRSA) and granulation and experiencing otalgia and dysgeusia. Computed tomography (CT) showed that the bony anterior and posterosuperior wall of the external auditory canal had been destroyed. The EACC was removed and Burow's solution instilled once a week, effecting a cure about one month later, le...Continue Reading

References

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Citations

Nov 22, 2013·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Chang Woo KimBum-Ki Cho

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