Abstract
Sirolimus-eluting stents (SESs), paclitaxel-eluting stents (PESs), and dexamethasone-eluting stents (DEXs) have anti-inflammatory properties; thus, the decreased in-segment restenosis rate observed with the use of these stents might be related to a weaker postprocedural inflammatory response. One hundred sixty consecutive patients with stable coronary artery disease who underwent successful single-vessel/lesion coronary artery stenting were prospectively studied. Thin-strut bare metal stents were deployed in 39 patients, SESs in 30, PESs in 61, and DEXs in 30. The 4 groups were similar with respect to demographic and angiographic variables and prevalence of risk factors. C-reactive protein (CRP) was measured at baseline and 24 and 48 hours after the procedure. Maximal increase in CRP was calculated as the increase in CRP at 48 hours/CRP compared with baseline. Angiographic follow-up was performed after 12.9 +/- 1.3 months or sooner, if needed, on the basis of clinical evidence. All patients presented a postprocedural increase in CRP that peaked at 48 hours (median 10.0 mg/L). Maximal CRP increase was similar across the 4 groups (medians 3.5 mg/L in the bare metal stent group, 3.6 mg/L in the SES group, 4.0 mg/L in the PES group...Continue Reading
References
Jul 31, 1987·The American Journal of Cardiology·R G MacdonaldC J Pepine
Feb 1, 1984·The Journal of Cell Biology·J P LongeneckerL K Johnson
Apr 1, 1997·Immunology·J K JacksonH M Burt
Jun 9, 1998·Heart·A H Gershlick, J Baron
Sep 2, 1998·The American Journal of Cardiology·A GaspardoneP A Gioffrè
Jan 13, 1999·Circulation·A FarbR Virmani
Jan 15, 2000·Journal of the American College of Cardiology·P H GreweK M Müller
Jun 22, 2000·Heart·Y HojoK Shimada
Nov 15, 2000·The American Journal of Cardiology·F VersaciP A Gioffrè
Jun 19, 2001·Annals of Medicine·I BelenkieJ V Tyberg
Sep 6, 2001·Circulation·T SuzukiA J Carter
Nov 6, 2001·Journal of the American College of Cardiology·D H WalterA M Zeiher
Dec 12, 2001·Journal of the American College of Cardiology·D H WalterA M Zeiher
Mar 1, 2002·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·W Warren SuhKirk N Garratt
Jun 26, 2002·Circulation·Andrew FarbRenu Virmani
Dec 12, 2002·Journal of the American College of Cardiology·Francesco VersaciUNKNOWN Immunosuppressive Therapy for the Prevention of Restenosis after Coronary Artery Stent Implantation Study
Apr 1, 2003·Circulation·Teruo InoueShigenori Morooka
Aug 9, 2003·Biochemical Pharmacology·María Jesús TuñónJavier González-Gallego
Jan 13, 2004·Journal of the American College of Cardiology·Daiju FukudaJunichi Yoshikawa
Jul 13, 2004·The American Journal of Cardiology·Rainer HoffmannPeter Hanrath
Dec 2, 2004·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Maria Fiammetta RomanoSalvatore Venuta
Feb 8, 2005·The American Journal of Cardiology·Giuseppe PattiGermano Di Sciascio
Mar 11, 2005·The American Journal of Cardiology·Jose M de la Torre-HernandezThierry Colman
Jul 19, 2005·Journal of the American College of Cardiology·Teruo InoueKoichi Node
Citations
Jul 12, 2011·Inflammation Research : Official Journal of the European Histamine Research Society ... [et Al.]·T I ArefievaE I Chazov
Dec 21, 2007·Cardiovascular and Interventional Radiology·Boris RadeleffGoetz M Richter
Dec 20, 2008·Cardiovascular Drugs and Therapy·Nuno M Pires, J Wouter Jukema
Jul 20, 2007·Cardiology in the Young·Elhadi H AburawiErkki Pesonen
Apr 23, 2009·European Heart Journal·Giampaolo NiccoliFilippo Crea
Feb 21, 2007·Heart·Duk-Woo ParkSeung-Jung Park
Mar 17, 2010·Future Cardiology·Rocco Antonio MontoneGiampaolo Niccoli
Jul 24, 2012·The Canadian Journal of Cardiology·Rami N KhouzamUzoma N Ibebuogu
Nov 28, 2006·Atherosclerosis·Nawsad Saleh, Per Tornvall
Mar 30, 2007·Journal of Interventional Cardiology·Flavio RibichiniCorrado Vassanelli
Aug 8, 2007·Journal of Interventional Cardiology·Natale Daniele BrunettiMatteo Di Biase
Mar 5, 2014·Journal of Interventional Cardiology·Shao-Liang ChenThach Nguyen
Oct 24, 2006·The American Journal of Cardiology·Atul Aggarwal
Nov 20, 2010·Journal of the American College of Cardiology·Giampaolo NiccoliFilippo Crea
Dec 14, 2011·Journal of the American College of Cardiology·Duk-Woo ParkSeung-Jung Park
Aug 20, 2014·Thrombosis Research·Rossella MarcucciRosanna Abbate
Sep 26, 2015·PloS One·I-Chang HsiehMing-Lung Tsai
Aug 18, 2010·Angiology·Mohsen MoohebatiGordon A Ferns
Jan 7, 2009·Therapeutic Advances in Cardiovascular Disease·Santiago Jimenez-ValeroJose López-Sendón
May 3, 2018·Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis·Zufar GabbasovVladimir Smirnov
Nov 4, 2009·Circulation·Duk-Woo ParkSeung-Jung Park
Dec 3, 2015·Journal of Cardiovascular Medicine·Francesco FracassiEmanuele Barbato
Apr 24, 2009·Coronary Artery Disease·Wei HuangZhong Zuo
Feb 6, 2014·Allergy & Rhinology·Nicholas G KounisGeorge Hahalis
Jul 3, 2021·Cells·Bradley TuckerSanjay Patel