C-reactive protein, glucose and iron concentrations are significantly altered in dogs undergoing open ovariohysterectomy or ovariectomy

Acta Veterinaria Scandinavica
Elena R MoldalJolle Kirpensteijn

Abstract

There are relatively few studies about the canine surgical stress response, a sequence of events orchestrated by the body in response to a surgical trauma which is sometimes, as shown in human surgery, deleterious to the patient. There is a need to identify objective markers to quantify this response in order to estimate tissue trauma and use the markers as potential early indicators of surgical complications. The study objective was to investigate the surgical stress response, measured by C-reactive protein (CRP), glucose and iron serum concentrations, to gonadectomy in female dogs, and to compare the response to ovariohysterectomy (OHE) with the response to ovariectomy (OVE). A randomized clinical trial was performed on a sample of 42 female dogs, which were divided into two groups: one group underwent OHE, the other OVE. Blood samples were collected immediately before surgery (T0), and at 1 (T1), 6 (T6), and 24 (T24) h after surgery, and serum frozen and stored at - 80 °C for later analysis. Upon thawing, the serum samples were subjected to measurement of CRP, glucose and iron concentration. Seventeen dogs in the OHE group and 19 dogs in the OVE group were included in the statistical analysis. There was a significant increas...Continue Reading

References

Aug 1, 1992·The British Journal of Surgery·R J BaigrieP J Morris
Jun 1, 1987·Critical Care Medicine·W M Stahl
Jan 1, 1988·Veterinary Research Communications·P D Eckersall, J G Conner
Jun 1, 1995·European Journal of Clinical Investigation·D H BiesmaJ J Marx
Jan 1, 1993·Veterinary Research Communications·S YamamotoM Naiki
Oct 1, 1993·The British Journal of Surgery·A J McMahonJ N Baxter
Feb 14, 1998·The British Journal of Surgery·C E van IperenA van de Wiel
Apr 25, 2000·World Journal of Surgery·H Kehlet
Aug 6, 2000·British Journal of Anaesthesia·J P Desborough
May 17, 2001·The Veterinary Record·L HoltonA Nolan
Jan 17, 2002·The New England Journal of Medicine·G van den BergheR Bouillon
Jul 4, 2002·American Journal of Surgery·Henrik Kehlet, Douglas W Wilmore
Jan 28, 2003·Diabetes Care·Baiju R Shah, Janet E Hux
Sep 27, 2003·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·S C RibeiroJ A Pinotti
Oct 16, 2003·JAMA : the Journal of the American Medical Association·Simon J FinneyTimothy W Evans
Nov 19, 2003·American Journal of Veterinary Research·Luc R BorerDavid E Spreng
Dec 23, 2003·Veterinary Surgery : VS·Ellen B DavidsonMark E Payton
Sep 7, 2004·Journal of the American Animal Hospital Association·Boel A FranssonClaude A Ragle
Oct 7, 2004·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·T M VriesendorpJ B L Hoekstra
Dec 3, 2004·ANZ Journal of Surgery·Mark Weatherall, Timothy J Maling
May 20, 2005·Veterinary Clinical Pathology·Jose Joaquýn CeronSilvia Martýnez-Subiela
Jul 13, 2005·Mayo Clinic Proceedings·Gunjan Y GandhiM Molly McMahon
Aug 12, 2006·The Veterinary Journal·R MischkeP D Eckersall
Mar 6, 2008·The Journal of Veterinary Medical Science·Masaaki NakamuraHajime Tsujimoto
Apr 28, 2009·Veterinary Clinical Pathology·Christine GriebschBarbara Kohn
Sep 29, 2009·Veterinary Surgery : VS·William T N CulpDorothy C Brown
Jan 5, 2011·Veterinary Clinical Pathology·Mads Kjelgaard-Hansen
Jan 18, 2011·Journal of the American Veterinary Medical Association·Marijke E Peeters, Jolle Kirpensteijn
Aug 29, 2012·American Journal of Veterinary Research·Elena R MoldalJolle Kirpensteijn
Aug 1, 2013·Veterinary Clinical Pathology·Mads Kjelgaard-HansenMichael Luntang-Jensen

❮ Previous
Next ❯

Citations

Jun 2, 2021·The Veterinary Clinics of North America. Small Animal Practice·Andrew L McGraw, Todd M Thomas

❮ Previous
Next ❯

Methods Mentioned

BETA
hysterectomy

Software Mentioned

Stata

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc
S CasellaG Piccione
The Canadian Veterinary Journal. La Revue Vétérinaire Canadienne
Amanda TallantSherisse A Sakals
© 2022 Meta ULC. All rights reserved