C-Reactive Protein in Peripheral Blood of Patients with Chronic and Aggressive Periodontitis, Gingivitis, and Gingival Recessions

Mediators of Inflammation
Stepan PodzimekJana Duskova

Abstract

CRP is a plasma protein that reflects a measure of the acute phase response to inflammation and is one of the markers of choice in monitoring this response. CRP can be used for the prediction and early detection of periodontal disease. The aim of this study was to compare and evaluate the systemic levels of CRP in the peripheral blood samples of patients with chronic and aggressive periodontitis, gingivitis, and gingival recessions and compare them with periodontal clinical parameters. All patients (N = 158) were examined prior to the initiation of periodontal treatment. Patients were divided into four groups. Group A consisted of 26 patients with aggressive periodontitis, Group B consisted of 111 patients with chronic periodontitis, Group C consisted of 13 patients with gingivitis, and Group D consisted of 8 patients with gingival recessions. Our study results indicate that CRP levels increase subsequently with the severity of the periodontal disease and that the bleeding on probing index showed much better positive correlation with the CRP levels compared to the pocket depth index in both periodontitis patients groups, especially in aggressive periodontitis patients.

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Citations

May 5, 2016·Disease Markers·Stepan PodzimekZdenek Broukal
Jul 2, 2016·Kidney Research and Clinical Practice·Jihyun YangWonyong Cho
Jun 22, 2018·Journal of Clinical Periodontology·Leonardo TrombelliDimitris N Tatakis
Jun 22, 2018·Journal of Periodontology·Leonardo TrombelliDimitris N Tatakis
Aug 3, 2019·Journal of Periodontology·Tiago TaieteRenato C Casarin
Oct 16, 2016·Medical Science Monitor : International Medical Journal of Experimental and Clinical Research·Gediminas ŽekonisJulija Narbutaitė
May 10, 2020·Periodontology 2000·Harvey A SchenkeinMariano Sanz
Dec 2, 2020·Journal of Clinical Periodontology·Fernando Oliveira CostaLuís Otávio Miranda Cota
Jun 22, 2017·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Georgios A KotsakisStefanos Tyrovolas
Apr 15, 2021·Critical Reviews in Clinical Laboratory Sciences·Christophe HirtzRui Vitorino
May 17, 2021·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Chunchun ChenFeiqi Zhu

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