C-reactive protein is associated with psychological risk factors of cardiovascular disease in apparently healthy adults

Psychosomatic Medicine
Edward C Suarez

Abstract

The current study examined the relation of anger, hostility, and severity of depressive symptoms, alone and in combination, to C-reactive protein (CRP) in healthy men and women. A high sensitivity enzyme linked immuno sorbent assay (ELISA) was used to evaluate CRP levels in a multiethnic sample of 127 healthy, nonsmoking men and women. Fasting blood samples were collected the same day the assessments were done of anger and hostility using the Buss-Perry Aggression Questionnaire (BPAQ) and depressive symptomatology using the Beck Depression Inventory (BDI). A psychological risk factor (PRF) score representing a composite summary indicator of BDI and BPAQ-anger and -hostility was generated using principal component analysis. Log-transformed CRP values were examined using univariate and multivariate analyses adjusting for control variables of age, gender, body mass index (BMI), alcohol use, exercise frequency, ratio of total to high-density lipoprotein cholesterol, and family history of premature coronary heart disease (CHD). Log-normalized CRP was correlated with BDI (r = 0.21, p =.02) and BPAQ anger (r = 0.20, p =.02), but not with BPAQ hostility. After adjustment for control variables, BDI (beta = 0.05, p =.011), BPAQ anger (be...Continue Reading

References

Oct 1, 1978·Circulation·J A BlumenthalL W Thompson
Sep 1, 1992·Journal of Personality and Social Psychology·A H Buss, M Perry
Aug 1, 1991·Medical Hypotheses·R S Smith
May 1, 1990·Molecular and Cellular Biology·T A Libermann, D Baltimore
Nov 1, 1989·The Journal of Nervous and Mental Disease·W T RileyM G Woods
Aug 1, 1974·The Journal of Nervous and Mental Disease·A P SchlessC Cochrane
Sep 1, 1971·The American Journal of Psychiatry·M M WeissmanE S Paykel
Mar 1, 1983·Psychosomatic Medicine·J C BarefootR B Williams
May 1, 1983·Psychosomatic Medicine·R B ShekelleO Paul
Feb 15, 1995·Circulation·N Frasure-SmithM Talajic
Jun 1, 1995·Scandinavian Journal of Immunology·A SeidelH Kirchner
Jul 21, 1995·Annals of the New York Academy of Sciences·A SłuzewskaK Wiktorowicz
Mar 1, 1996·Psychological Bulletin·T Q MillerA J Hallet
Apr 3, 1997·The New England Journal of Medicine·P M RidkerC H Hennekens
Apr 10, 1997·The New England Journal of Medicine·P J Barnes, M Karin
Jul 1, 1997·The Journal of Laboratory and Clinical Medicine·B JilmaO F Wagner
Dec 12, 1997·Journal of Psychosomatic Research·M BerkA O'Neill-Kerr
Jan 20, 1998·The American Journal of Psychiatry·A H Glassman, P A Shapiro
Apr 18, 1998·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·K C LightM T Allen
Jun 12, 1998·JAMA : the Journal of the American Medical Association·B W PenninxR B Wallace
Jul 17, 1998·Archives of Internal Medicine·D E FordM J Klag
Jul 29, 1998·Circulation·R L Johnson
Jan 14, 1999·The New England Journal of Medicine·R Ross
Jun 22, 1999·Circulation·J T Willerson
Sep 14, 1999·Circulation·P Libby, P M Ridker
Oct 28, 1999·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·S K LutgendorfD M Lubaroff
Nov 24, 1999·Biological Psychiatry·K J Ressler, C B Nemeroff
May 16, 2000·Archives of Internal Medicine·F LespéranceP Théroux
Jun 14, 2000·Annals of Medicine·T W Du Clos
Aug 19, 2000·Psychosomatic Medicine·B S Jonas, M E Mussolino
Nov 25, 2000·Journal of the American College of Cardiology·P AngererC von Schacky
Mar 20, 2001·Archives of General Psychiatry·B W PenninxW van Tilburg

❮ Previous
Next ❯

Citations

Aug 13, 2008·Social Psychiatry and Psychiatric Epidemiology·Hynek PikhartMartin Bobak
Feb 25, 2010·International Journal of Behavioral Medicine·Michael ChaitonMarie Lambert
Mar 12, 2010·Psychological Medicine·S Goldman-MellorA Steptoe
Jul 16, 2011·Development and Psychopathology·Shelley E TaylorTeresa E Seeman
Jul 19, 2006·Health Psychology : Official Journal of the Division of Health Psychology, American Psychological Association·Edward C Suarez
Feb 1, 2012·Molecular Psychiatry·C L Raison, A H Miller
Sep 27, 2006·JAAPA : Official Journal of the American Academy of Physician Assistants·Matthias M Goldstein
May 4, 2011·Psychosomatic Medicine·Allison A AppletonLaura D Kubzansky
Dec 17, 2008·Genes, Brain, and Behavior·P SuchankovaA Ekman
Aug 25, 2007·Annual Review of Clinical Psychology·Timothy W Smith, Justin MacKenzie
Apr 4, 2008·Behavioral and Brain Functions : BBF·Susanne HenningssonAgneta Ekman
Feb 26, 2008·European Archives of Psychiatry and Clinical Neuroscience·Angelo B CunhaFlávio Kapczinski
Oct 13, 2014·Journal of Psychiatric Research·Thomas B CookTeodor T Postolache
Aug 7, 2008·Journal of Women's Health·Esben Strodl, Justin Kenardy
Jul 1, 2011·Psychosomatic Medicine·Alanna Amyre MorrisViola Vaccarino
May 17, 2006·Annals of Behavioral Medicine : a Publication of the Society of Behavioral Medicine·Edward C Suarez, K Ranga R Krishnan
Apr 10, 2010·Annals of Behavioral Medicine : a Publication of the Society of Behavioral Medicine·Julia D Betensky, Richard J Contrada
Feb 26, 2013·Annals of Behavioral Medicine : a Publication of the Society of Behavioral Medicine·Diana A ChirinosNeil Schneiderman
Oct 20, 2012·Brain, Behavior, and Immunity·William B MalarkeyMaryanna Klatt
Jul 7, 2012·Social Science & Medicine·Christopher R BrowningJames Iveniuk
Mar 23, 2011·Biological Psychology·Marko ElovainioLiisa Keltikangas-Järvinen
May 12, 2009·Biological Psychology·Carissa A LowMary Chester M Wasko
Dec 7, 2007·Primary Care·Donald M HiltyHendry Ton
Sep 1, 2007·Progress in Neuro-psychopharmacology & Biological Psychiatry·Kosuke NaritaYuji Wada
Jan 13, 2006·European Journal of Clinical Investigation·J J PuderU Keller
Apr 10, 2013·Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG·Agata KurekSylke Schneider-Burrus
May 16, 2006·Gastroenterology·Ashwin K VargheseStephen M Collins
Feb 27, 2015·Annals of Behavioral Medicine : a Publication of the Society of Behavioral Medicine·Jennifer Morozink BoylanCarol D Ryff
May 11, 2011·Brain, Behavior, and Immunity·S ShivpuriG A Talavera
Aug 14, 2012·Brain, Behavior, and Immunity·Denise Janicki DevertsKaren A Matthews
Apr 22, 2014·Journal of Psychosomatic Research·Julie Boisclair DemarbleBianca D'Antono

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiovascular Disease Pathophysiology

Cardiovascular disease involves several different processes that contribute to the pathological mechanism, including hyperglycemia, inflammation, atherosclerosis, hypertension and more. Vasculature stability plays a critical role in the development of the disease. Discover the latest research on cardiovascular disease pathophysiology here.