C-reactive protein may be a prognostic factor for the whole gastroenteropancreatic neuroendocrine tumor group

World Journal of Gastrointestinal Oncology
Ömer KomaçMesut Akarsu

Abstract

Long non-coding RNAs (lncRNAs) are a kind of single-stranded RNA of more than 200 nucleotides in length and have no protein-coding function. Amounting studies have indicated that lncRNAs could play a vital role in the initiation and development of cancers, including gastric cancer (GC). Considering the crucial functions of lncRNAs, the identification and exploration of novel lncRNAs in GC is necessary. To identify independent prognostic markers for the whole gastroenteropancreatic neuroendocrine tumor (GEP-NET) group. Ninety-three patients diagnosed with GEP-NETs within a specified period were included in this study. Patient data were retrospectively analyzed. The relationships between all independent variables and 5-year survival status calculated during the follow-up period (months) were assessed. In addition, the relationships between the independent variables were investigated. When 5-year survival rate was compared, a statistically significant relationship between the age at diagnosis, male gender, tumor size, tumor stage, liver and/or distant metastasis, and tumor grade determined by the Ki-67 level and mitotic count, and the level of C-reactive protein (CRP), was observed. The mean survival (overall survival) of the stud...Continue Reading

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Methods Mentioned

BETA
surgical resection
ESR
biopsy

Software Mentioned

NET
GEP

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