C-reactive Protein/Albumin Ratio and Acute Kidney Injury after Radical Cystectomy among Elderly Patients: A Propensity Score-Matched Analysis.

Disease Markers
Jihion YuYoung-Kug Kim

Abstract

The C-reactive protein (CRP)/albumin ratio is a useful index used to represent patient inflammation and nutritional status. Elderly patients are at the highest risk for acute kidney injury (AKI). We clarified the impact of the preoperative CRP/albumin ratio on AKI and evaluated the impact of postoperative AKI on end-stage renal disease (ESRD) among elderly cystectomy patients. We included elderly patients ≥ 65 years of age who underwent radical cystectomy. Multivariate logistic regression analysis and receiver operating characteristic curve analysis were performed to identify risk factors for AKI. Propensity score-matched analysis and conditional logistic regression analysis were performed to elucidate the impact of the CRP/albumin ratio on AKI. The incidence of ESRD was compared between the non-AKI and AKI groups at 12 months after radical cystectomy. AKI occurred in 110 patients (32.2%). The CRP/albumin ratio and 6% hydroxyethyl starch amount were risk factors for postoperative AKI. The optimal cut-off value for the CRP/albumin ratio predicting AKI was 0.1. After propensity score matching, the AKI incidence in the CRP/albumin ratio ≥ 0.1 group was higher than that in the CRP/albumin ratio < 0.1 group (46.7% vs. 20.6%, P < 0.0...Continue Reading

References

Jul 1, 1996·Renal Failure·F SantacruzN Breuer
Dec 16, 1998·Kidney International·R A Star
May 8, 2004·Experimental Gerontology·Karen Suárez KrabbeHelle Bruunsgaard
Dec 2, 2004·Blood·Luigi FerrucciDan L Longo
Jan 22, 2005·Seminars in Dialysis·Burl R Don, George Kaysen
Mar 19, 2005·Circulation Research·Radjesh J BisoendialErik S G Stroes
Mar 22, 2008·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·G Morris-StiffK R Prasad
Oct 22, 2008·The Journal of Urology·Brian R LaneAndrew C Novick
Nov 21, 2008·Journal of the American Society of Nephrology : JASN·Areef IshaniAllan J Collins
Feb 27, 2009·Critical Care Medicine·Jean-Philippe RiouxStéphan Troyanov
Mar 11, 2009·Clinical Medicine : Journal of the Royal College of Physicians of London·Emily FaircloughClive Kelly
May 6, 2009·Annals of Internal Medicine·Andrew S LeveyUNKNOWN CKD-EPI (Chronic Kidney Disease Epidemiology Collaboration)
Sep 22, 2009·Clinics in Geriatric Medicine·Khaled Abdel-Kader, Paul M Palevsky
Feb 25, 2010·Annals of Surgical Oncology·Stephen B Edge, Carolyn C Compton
Mar 30, 2010·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Steven G Coca
Oct 30, 2010·Critical Care : the Official Journal of the Critical Care Forum·Christian J WiedermannMichael Joannidis
Apr 19, 2011·The Journal of Urology·In Gab JeongChoung-Soo Kim
Nov 12, 2014·BMJ : British Medical Journal·Christiane S HartogKonrad Reinhart
Nov 13, 2015·Journal of the American Society of Nephrology : JASN·Hamid RabbUNKNOWN Acute Dialysis Quality Initiative Consensus XIII Work Group
Nov 26, 2015·Intensive Care Medicine·M E O'ConnorJ R Prowle
Dec 15, 2015·British Journal of Anaesthesia·O Goren, I Matot
Apr 5, 2016·European Journal of Anaesthesiology·Gernot MarxMichaela Eikermann
Sep 7, 2016·European Journal of Internal Medicine·Andrea TicinesiTiziana Meschi
May 10, 2017·European Urology·Marko Babjuk
Jul 25, 2017·Journal of Clinical Gastroenterology·David J GibsonGlen A Doherty

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Citations

Apr 10, 2021·Burns : Journal of the International Society for Burn Injuries·Jihion YuYoung-Kug Kim

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