PMID: 6980631Aug 1, 1982Paper

C2 deficient systemic lupus erythematosus: its association with anti-Ro (SSA) antibodies

Archives of Dermatology
P R VandersteenF C McDuffie

Abstract

C2 deficiency is the most common complement component deficiency. While individuals with C2 deficiency may be completely normal, a lupus erythematosus-like disease process has developed in some. A 28-year-old woman had a chronic photodermatitis, arthralgias, and mesangial lupus nephritis, She has C2 deficiency associated with an HLA-Dw2 transplantation antigen. Her serum has shown antibodies to the macromolecule Ro (the A antigen in Sjögren's syndrome), while failing to demonstrate antinuclear antibodies in routine laboratory determinations.

Citations

Jan 1, 1986·Springer Seminars in Immunopathology·V Agnello
Jul 1, 1985·Clinics in Dermatology
Nov 1, 1991·The British Journal of Dermatology·G M Murphy, J L Hawk
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