C3c and C3d fragments of human C3 bind myeloma IgG1 and IgG3 proteins

Immunology Letters
A HautanenI Seppälä

Abstract

Eight human myeloma proteins, two of each IgG subclass, were studied for binding to solid-phase C3c and C3d by the ELISA technique. Myeloma IgG1 kappa, IgG1 lambda, IgG3 kappa and IgG3 lambda proteins bound to C3c and C3d, while two IgG2 kappa, and two IgG4 kappa proteins failed to show significant binding affinity. The results suggest that like C1q, the stable binding sites of C3, located on the C3c and C3d parts of the molecule, have affinity for IgG subclasses 1 and 3.

References

Jan 1, 1979·Advances in Immunology·A N Theofilopoulos, F J Dixon
Aug 1, 1978·Proceedings of the National Academy of Sciences of the United States of America·R D SchreiberH J Müller-Eberhard
Jan 1, 1979·Advances in Protein Chemistry·R R Porter, K B Reid
Aug 1, 1978·The Journal of Clinical Investigation·M TakahashiV Nussenzweig
Feb 1, 1975·Proceedings of the National Academy of Sciences of the United States of America·G W Miller, V Nussenzweig
Dec 1, 1968·The Australian Journal of Experimental Biology and Medical Science·J D Young, E W Kraegen
Jan 1, 1980·Advances in Immunology·H J Müller-Eberhard, R D Schreiber
Dec 1, 1981·The Journal of Experimental Medicine·T FujitaN Tamura
Dec 1, 1980·Proceedings of the National Academy of Sciences of the United States of America·S K LawR P Levine
Feb 1, 1980·Molecular Immunology·R A Harrison, P J Lachmann
Jan 1, 1980·Journal of Immunological Methods·C DavrincheL Rivat-Peran

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Citations

Jan 1, 1987·Journal of Reproductive Immunology·D S TorryP R McConnachie
Jun 1, 1989·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·P KurkiI Virtanen
Mar 1, 1983·Scandinavian Journal of Immunology·A Hautanen, J Keski-Oja
Jun 1, 1983·Scandinavian Journal of Immunology·A SarnestoO Mäkelä

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