Ca2+-binding glycoprotein in avian bone induced by estrogen

Connective Tissue Research
N StagniM Zanetti

Abstract

The discovery in calcifying cartilage of a glycoprotein, endowed with high calcium affinity and alkaline phosphatase activity, has prompted the investigation of the presence of this compound in other calcified tissues. From medullary bone, a tissue which is highly mineralized under estrogen stimulus, a glycoprotein has been extracted which had the properties described. Besides the high calcium affinity (KD = 10(-7)M), this protein shows phosphatase activity and rate of hydrolysis of ATP, GTP and pyrophosphate was measured. Analysis of the chemical composition of the matrix of the medullary bone indicates that proteoglycans are present in large amounts. The calcium binding glycoprotein appears to be a compound present in different calcified tissues.

References

Nov 1, 1979·Calcified Tissue International·N StagniB de Bernard
Dec 22, 1976·Calcified Tissue Research·J D Termine, K M Conn
Dec 28, 1977·Calcified Tissue Research·R T Turner, H Schraer
May 26, 1978·Calcified Tissue Research·M T Dimuzio, A Veis
May 1, 1977·Calcified Tissue Research·B De BernardM Zanetti
May 1, 1977·Calcified Tissue Research·M Jontell, A Linde
May 1, 1977·Calcified Tissue Research·A G LeaverI B Holbrook
May 1, 1977·Calcified Tissue Research·J AlthoffH J Höhling
Nov 17, 1975·Cell and Tissue Research·E Bonucci, G Gherardi
Sep 1, 1967·Journal of Ultrastructure Research·E Bonucci
Jan 1, 1970·Calcified Tissue Research·M C PugliarelloA Ascenzi
Sep 15, 1971·Comparative Biochemistry and Physiology. B, Comparative Biochemistry·J K Candlish, F J Holt
Feb 29, 1972·Biochimica Et Biophysica Acta·F VitturB De Bernard
Jul 11, 1972·Biochemical and Biophysical Research Communications·F VitturB De Bernard
Jan 1, 1973·Calcified Tissue Research·M C PugliarelloA Ascenzi
Nov 1, 1970·Proceedings of the National Academy of Sciences of the United States of America·S Y AliH C Anderson
Jan 1, 1969·Calcified Tissue Research·A Z Zallone, W J Mueller
Jun 1, 1961·The American Journal of Physiology·H FLEISH, W F NEUMAN
Jun 1, 1963·Journal of Ultrastructure Research·A ASCENZI BOCCIARELLIDS

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Citations

Mar 15, 2005·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·Xibin WangRoland M Leach
Jan 1, 1980·Calcified Tissue International·B de BernardA Teti
Sep 1, 1981·Archives internationales de physiologie et de biochimie·N Fontaine
Jan 1, 1986·Ultrastructural Pathology·A StarkJ L Ericsson

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