Ca2+ regulation and gene expression in normal brain aging

Trends in Neurosciences
Emil C ToescuPhilip W Landfield

Abstract

Understanding the cellular mechanisms that characterize the functional changes of the aged brain is an ongoing and formidable challenge for the neuroscience community. Evidence now links changes in Ca(2+) influx and homeostasis with perturbations induced by the aging process in the function of the main intracellular organelles involved in Ca(2+) regulation: the endoplasmic reticulum and mitochondria. New perspectives are also offered by recent gene microarray studies, illustrating the multifactorial nature of the aging process.

References

Aug 2, 1994·Proceedings of the National Academy of Sciences of the United States of America·M TerasakiT S Reese
Feb 1, 1997·Trends in Biochemical Sciences·H L Pahl, P A Baeuerle
May 28, 1998·The Journal of Biological Chemistry·G P DaveyJ B Clark
Nov 18, 2000·The Journal of Physiology·M R Duchen
Dec 15, 2000·Cell Calcium·E C ToescuA Verkhratsky
Apr 20, 2001·Trends in Neurosciences·O H PetersenM K Park
Sep 27, 2001·Proceedings of the National Academy of Sciences of the United States of America·A E WestM E Greenberg
May 17, 2002·Progress in Neurobiology·Pankaj Sah, E S Louise Faber
May 23, 2002·Biochimie·Hans Friberg, Tadeusz Wieloch
Aug 2, 2002·European Journal of Pharmacology·Alexej Verkhratsky, Ole H Petersen
Aug 2, 2002·European Journal of Pharmacology·Gregory V ClodfelterOlivier Thibault
Jan 25, 2003·Cell Calcium·Michael J Berridge
May 22, 2003·Progress in Neurobiology·Ephron S Rosenzweig, Carol A Barnes
Jul 3, 2003·Nature Reviews. Molecular Cell Biology·Michael J BerridgeH Llewelyn Roderick
Feb 18, 2004·Aging Cell·David G Nicholls

❮ Previous
Next ❯

Citations

Jan 19, 2006·Proceedings of the National Academy of Sciences of the United States of America·Alexei V Samsonovich, Giorgio A Ascoli
Aug 12, 2014·Age·Brandon H CherryRobert T Mallet
May 6, 2005·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Christopher M NorrisSusan D Kraner
Dec 3, 2005·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Emil C Toescu
Feb 8, 2006·Postgraduate Medical Journal·R Peters
Mar 23, 2006·Nature Reviews. Neuroscience·Mark P Mattson, Tim Magnus
Feb 28, 2009·PloS One·Elsa DiguetEmmanuel Brouillet
May 15, 2009·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Lawrence D BrewerEric M Blalock
Jan 5, 2011·PloS One·Brian P HeadHemal H Patel
May 4, 2011·Nutritional Neuroscience·Linnea R FreemanAnn-Charlotte Granholm
Jun 20, 2012·Gerontology·Ambrose R Kidd Iii, Jianxin Bao
Oct 31, 2012·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Andras Bilkei-Gorzo
May 30, 2013·PloS One·Eun Ju LeeInho Choi
Oct 29, 2010·Journal of Molecular Neuroscience : MN·Alessio CrestiniAnnamaria Confaloni
Jun 22, 2006·Acta Pharmacologica Sinica·He-ping ChengAlexei Verkhratsky
Oct 22, 2008·Toxicological Sciences : an Official Journal of the Society of Toxicology·Zhen LiJoyce Royland
Feb 12, 2011·Journal of Bioenergetics and Biomembranes·Julia Toman, Gary Fiskum
Oct 31, 2015·Current Opinion in Pharmacology·Alexei VerkhratskyVladimir Parpura
Feb 16, 2011·Brain, Behavior, and Immunity·Susanna Rosi
Jan 15, 2010·Trends in Neurosciences·Sara N Burke, Carol A Barnes
Jun 9, 2009·The Journal of Steroid Biochemistry and Molecular Biology·Tiina KeisalaPentti Tuohimaa
May 12, 2009·Neuroscience Research·Yasuto KashiyaeManabu Sakakibara
Aug 5, 2008·Trends in Neurosciences·Ilya Bezprozvanny, Mark P Mattson
May 20, 2008·Experimental Gerontology·Ladislav OudaJosef Syka
Nov 15, 2006·Neurobiology of Aging·Stella TrompetAnton J M de Craen
Sep 15, 2005·Journal of Neurochemistry·Ian F SmithFrank M LaFerla
Aug 19, 2009·Annals of the New York Academy of Sciences·Shuying Wang, Kathryn M Albers
May 23, 2007·Aging Cell·David Murchison, William H Griffith

❮ Previous
Next ❯

Related Concepts

Related Feeds

Calcium & Bioenergetics

Bioenergetic processes, including cellular respiration and photosynthesis, concern the transformation of energy by cells. Here is the latest research on the role of calcium in bioenergetics.

© 2021 Meta ULC. All rights reserved