Cadaveric lobar lung transplantation: technical aspects

The Annals of Thoracic Surgery
Silvana F MarascoGeraldine A Lee

Abstract

The use of lobar transplantation and other size reduction techniques has allowed larger donor lungs to be utilized for smaller recipients who tend to have longer waiting times for transplantation. However, despite these advantages, the techniques have not been widely adopted. We outline the surgical and sizing issues associated with this technique. A retrospective review of 23 consecutive patients who received lung transplantation with anatomic lobar reduction was performed, focusing on surgical technique and outcomes. All 23 patients received an anatomic lobar reduction of between 1 and 3 lobes. Survival analysis showed no difference between the lobar reduction cohort and the other historically comparable lung transplant patients from our institution (p=0.115). Percent predicted forced vital capacity and forced expiratory volume in 1 second at 3 months correlated with transplanted donor to recipient total lung capacity ratio, confirming the importance of correct sizing. Anatomic lobar reduction in lung transplantation is a safe and effective means of transplanting pediatric and small adult recipients, and urgently listed patients.

References

Mar 1, 1997·The Journal of Thoracic and Cardiovascular Surgery·J P CouetilA F Carpentier
Jul 29, 1999·The Journal of Thoracic and Cardiovascular Surgery·O ArtemiouW Klepetko
Dec 18, 2001·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·T OtoN Simizu
Jan 30, 2004·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Clemens AignerWalter Klepetko
Feb 1, 2005·The Annals of Thoracic Surgery·Michael E BowdishMark L Barr
Oct 13, 2006·Pediatric Transplantation·Stuart C Sweet
Apr 22, 2009·The Journal of Thoracic and Cardiovascular Surgery·David P MasonEugene H Blackstone
Oct 2, 2009·Pediatric Transplantation·Carsten MuellerMartin Strueber
Jan 2, 2010·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Dominic T KeatingGregory I Snell

❮ Previous
Next ❯

Citations

Jul 26, 2013·The New England Journal of Medicine·Keren Ladin, Douglas W Hanto
Oct 24, 2012·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Ilhan InciWalter Weder
Nov 30, 2012·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Ankit Bharat, G Alexander Patterson
Aug 1, 2013·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Clemens Aigner
Aug 1, 2013·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Delphine MitilianUNKNOWN Foch Lung Transplant Group
Sep 23, 2014·Transplantation Proceedings·M NosottiL Santambrogio
Nov 13, 2013·Seminars in Thoracic and Cardiovascular Surgery·Norihisa ShigemuraJonathan D'Cunha
Jul 3, 2013·The Annals of Thoracic Surgery·Michael EberleinChristian A Merlo
Jun 19, 2013·The Annals of Thoracic Surgery·Norihisa ShigemuraChristian A Bermudez
Dec 24, 2015·Pediatric Transplantation·Jessica G Y Luc, Jayan Nagendran
Dec 18, 2013·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·S C Sweet, M L Barr
Sep 5, 2014·Respirology : Official Journal of the Asian Pacific Society of Respirology·Bruce Robert ThompsonGregory Ian Snell
May 9, 2014·Transplant International : Official Journal of the European Society for Organ Transplantation·Alexis SlamaClemens Aigner
Jul 21, 2015·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·B J LevveyG I Snell
Aug 5, 2015·Lung·Don HayesCarol K Conrad
Jul 19, 2016·Medical Science Monitor Basic Research·Anton SabashnikovFabio De Robertis
Aug 12, 2015·Current Opinion in Organ Transplantation·Jeremie ReebMarcelo Cypel
Jun 2, 2020·Pediatric Transplantation·Thomas MartensNagarajan Muthialu
Jun 27, 2020·Interactive Cardiovascular and Thoracic Surgery·João Santos SilvaPierre-Emmanuel Falcoz
Jan 22, 2021·Annals of Thoracic and Cardiovascular Surgery : Official Journal of the Association of Thoracic and Cardiovascular Surgeons of Asia·Ilhan InciWalter Weder
Jul 30, 2020·The Journal of Thoracic and Cardiovascular Surgery·Jose Luis Campo-Canaveral De La CruzLaura Donahoe
Aug 7, 2021·The Journal of Thoracic and Cardiovascular Surgery·Marco SchiavonUNKNOWN Lung Transplantation Working Group

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation
Dominic T KeatingGregory I Snell
European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery
Ilhan InciWalter Weder
American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Gregory I SnellF Rosenfeldt
American Journal of Respiratory and Critical Care Medicine
E GabbayGregory I Snell
© 2021 Meta ULC. All rights reserved