Cadmium and Lead in Women Who Miscarried

Clinical Laboratory
Wioleta J OmeljaniukMaria H Borawska

Abstract

Cadmium (Cd) and lead (Pb) are toxic elements which, when ingested excessively in food and drinking water, accumulate in selected organs and pass through the placenta barrier to the foetus, showing teratogenic effects. The aim of the study was to determine the concentration of Cd and Pb in blood and placental tissue in women who miscarried. The study group consisted of 83 women who miscarried. The control group included 35 women in the first trimester of pregnancy and after childbirth. The experimental materials consisted of whole blood and fragments of placental tissue. The concentrations of Cd and Pb were determined using atomic absorption spectrometry (AAS) with electrothermal atomization in a graphite furnace and by Inductively Coupled Plasma Mass Spectrometry (ICP-MS) in standard mode. The average concentration of Cd (2.730 ± 2.07 µg/L) and Pb (35.54 ± 11.0 µg/L) in the blood of women with miscarriage was higher in comparison to the level of these toxic metals in the blood of women from the control group (Cd 1.035 ± 0.59 µg/L; Pb 27.11 ± 4.6 µg/L). The average Cd (214.4 ± 514 µg/L) and Pb (199.6 ± 348 µg/L) content in the placenta of women with miscarriage was higher in comparison to the amount of these elements in the pla...Continue Reading

Citations

Jun 24, 2020·International Journal of Environmental Research and Public Health·Angelika Edyta Charkiewicz, Jeffrey R Backstrand
Jan 16, 2021·International Journal of Environmental Research and Public Health·Rasheda KhanamAbdullah H Baqui
Dec 19, 2020·International Journal of Environmental Research and Public Health·Alessandra RossiMelissa Harclerode
Mar 3, 2021·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Jin LiuWenchang Zhang

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