Cadmium stress alters gene expression of DNA mismatch repair related genes in Arabidopsis seedlings

Chemosphere
Wan LiuQ Zhang

Abstract

Cadmium (Cd) is a non essential element, and is a widespread environmental pollutant. Exposure to Cd can result in a variety of adverse health effects in plant and humans. In the current study, Arabidopsis seedlings were used as a bio-indicator of Cd pollution. Seedlings were grown on MS media containing 0-6.0 mg L(-1) Cd for 18 days, and the gene expression patterns were used to link increased Cd exposure with progressive biological effects. Reduction of total soluble protein content in shoots of the Arabidopsis seedlings occurred with increase in Cd concentrations. For the gene expression patterns, seven genes known to be involved in cell division and DNA mismatch repair (MMR) system were investigated by semi-quantitative RT-PCR, and normalized using 18S rRNA gene expression. Expression of the proliferating cell nuclear antigen 2 (atPCNA 2), MutS 3 homolog (atMSH 3) and MutL1 homolog (atMLH1) genes in shoots of Arabidopsis was strongly induced by exposure to 0.75 mg L(-1) Cd, but were repressed by other Cd concentrations whereas exposure to 0.75-6 mg L(-1) of Cd resulted in a decreased expression of atPCNA1, atMSH 2, 6 and 7 genes independently of any observable biological effects, including survival, fresh weight and chlorop...Continue Reading

References

Apr 29, 2000·Archives of Environmental Contamination and Toxicology·C K WongM H Wong
Jul 9, 2002·Environmental Science & Technology·Sandra CitterioAngela Santagostino
Jun 11, 2003·Nature Genetics·Yong Hwan JinDmitry A Gordenin
Jul 23, 2003·Environmental and Molecular Mutagenesis·Anna M JelasoCharles F Ide
Sep 24, 2004·Bulletin of Environmental Contamination and Toxicology·X XiongJ Peterson
Dec 16, 2004·Environmental Science & Technology·Stephen R StürzenbaumPeter Kille
Feb 22, 2005·Environmental Research·Anna M JelasoCharles F Ide
Apr 5, 2005·Journal of Plant Research·Taichi YamamotoKengo Sakaguchi
Jul 30, 2005·Environmental Toxicology and Chemistry·Tariq A AkhtarBruce M Greenberg
Oct 15, 2005·Ecotoxicology and Environmental Safety·Tomás GichnerKaterina Demnerová
Jan 26, 2006·Environmental Science & Technology·Christopher W TheodorakisC Brandon Law
May 11, 2006·Environmental Science & Technology·F BrulleF Vandenbulcke
Jul 25, 2006·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·Julie Gauley, John J Heikkila
Oct 25, 2006·The Plant Journal : for Cell and Molecular Biology·Ayako NishizawaShigeru Shigeoka

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Citations

Nov 8, 2011·Journal of Experimental Botany·Maria GrecoMaria Beatrice Bitonti
Mar 16, 2016·Environmental Science and Pollution Research International·Dongyu XuBo Gao

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