Caenorhabditis elegans ADAR editing and the ERI-6/7/MOV10 RNAi pathway silence endogenous viral elements and LTR retrotransposons

doi:10.1101/825315

Caenorhabditis elegans ADAR editing and the ERI-6/7/MOV10 RNAi pathway silence endogenous viral elements and LTR retrotransposons

bioRxiv

Oct 31, 2019

Sylvia E J Fischer, Gary B Ruvkun

DOI: 10.1101/825315

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Abstract

Endogenous retroviruses and LTR retrotransposons are mobile genetic elements that are closely related to retroviruses. Desilenced endogenous retroviruses are associated with human autoimmune disorders and neurodegenerative diseases. C. elegans and related Caenorhabdites contain LTR retr...read more

Mentioned in this Paper

Adenosine Deaminase

Antiviral Agents

Autoimmune Diseases

Genes

Genes, Viral

Nerve Degeneration

Retroviridae

RNA, Double-Stranded

RNA, Viral

Virus Diseases

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