Caffeine- and kallikrein-induced stimulation of human sperm motility: a comparative study.

Andrologia
W B Schill

Abstract

Stimulation of human sperm motility by caffeine and kallikrein was compared in the same semen material. Caffeine, a cyclic nucleotide phosphodiesterase inhibitor, induced an immediate stimulation of sperm motility the intensity being relatively constant during the first two hours of incubation. Kallikrein, a kinin-releasing proteinase, induced a similar enhancement of total sperm motility, but showed a delayed type of reaction with maximum stimulation at 2 hours of incubation. In contrast to the effect of caffeine lasting some hours, enhancement of sperm motility induced by kallikrein was observed 24 hours. Simultaneous addition of serum (kininogen source) and kallikrein to semen samples led to a sitmulation of total sperm motility with higher mean values than those obtained by caffeine of kallikrein alone. However, the ratio of spermatozoa with very good forward progression was highest during caffeine stimulation. Simultaneous addition of caffeine and kallikrein led to a further improvement of sperm motility which was significantly above that produced by caffeine or kallikrein alone. This observation and the finding of a different response of the spermatozoa of two ejaculates towards caffeine of kallikrein indicate that caffei...Continue Reading

References

Aug 31, 1973·Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character·J S Tash, T Mann
Jul 27, 1970·Biochemical and Biophysical Research Communications·E R Casillas, D D Hoskins
May 18, 1971·Biochimica Et Biophysica Acta·D D HoskinsE R Casillas
Nov 1, 1971·Archives of Biochemistry and Biophysics·E R Casillas, D D Hoskins
Dec 1, 1972·Biology of Reproduction·A SosaA Rosado
Sep 1, 1973·Fertility and Sterility·A Haesungcharern, M Chulavatnatol
Oct 1, 1973·Fertility and Sterility·C SchoenfeldL Dubin

❮ Previous
Next ❯

Citations

Jul 20, 1979·Archives of Gynecology·W B Schill
Mar 1, 1980·Archives of Andrology·S J MultamäkiB M Djupsund
Jan 1, 1995·International Urology and Nephrology·S AydinB Alagöl
Jan 1, 1996·International Urology and Nephrology·S AydinG Dellaloğlu
Jan 1, 1988·Archives of Andrology·S Saito, Y Kumamoto
Jul 20, 2007·The Cochrane Database of Systematic Reviews·P VandekerckhoveE Hughes
Dec 1, 1995·European Journal of Biochemistry·F EspañaK Witzgall
Dec 19, 2007·Asian Journal of Andrology·F DimitriadisN Sofikitis
May 5, 2000·The Cochrane Database of Systematic Reviews·P VandekerckhoveE Hughes
Dec 25, 2013·International Journal of Biological Macromolecules·Sanjay KumarSavita Yadav
Feb 23, 1999·The Urologic Clinics of North America·A T Chuang, S S Howards

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.