Caffeine abstinence augments the systolic blood pressure response to adenosine in humans

The American Journal of Cardiology
Gerard A RongenJ S Floras

Abstract

Blood pressure and heart rate responses to adenosine infusion (35, 70, and 140 microg/kg/min, intravenously) were studied in 7 healthy men after 6, 30, 78, 150, and 318 hours of abstinence from regular caffeine use. The finding that caffeine abstinence augmented the systolic pressor response (from -1 +/- 2 mm Hg at 6 hours to +9 +/- 2 mm Hg at 318 hours; p = 0.01) but not the tachycardic response to adenosine has implications for current clinical and research applications of this purine.

References

Mar 1, 1992·Circulation·S W Ely, R M Berne
May 1, 1991·Circulation·I BiaggioniD Robertson
Dec 1, 1987·Acta Physiologica Scandinavica·T B ConradsonP J Barnes
Dec 1, 1987·British Journal of Clinical Pharmacology·P SmitsT Thien
Mar 1, 1987·British Journal of Clinical Pharmacology·P G ReidA P Smith
Mar 1, 1987·Acta Physiologica Scandinavica·T B ConradsonP J Barnes
Sep 1, 1987·British Journal of Clinical Pharmacology·R W FullerP J Barnes
Aug 1, 1994·Clinical Science·A EdlundA Sollevi
Feb 1, 1994·Journal of the American College of Cardiology·M D CerqueiraA S Iskandrian
Apr 1, 1993·Naunyn-Schmiedeberg's Archives of Pharmacology·B JohanssonB B Fredholm

❮ Previous
Next ❯

Citations

Dec 29, 2010·International Journal of Vascular Medicine·Darío EcheverriAngélica Prieto
Jun 1, 2012·Journal of Caffeine Research·Catherine F Notarius, John S Floras
Dec 4, 2008·Pharmacology & Therapeutics·Niels P RiksenPaul Smits
Feb 25, 2011·European Journal of Heart Failure·Harindra C WijeysunderaJohn S Floras
May 29, 2004·The American Journal of Cardiology·Kumiko HirataJunichi Yoshikawa
Apr 21, 2006·Journal of Cardiac Failure·Catherine F NotariusJohn S Floras
Apr 18, 2008·European Journal of Pharmacology·Niels P RiksenPaul Smits
Aug 13, 2003·Circulation·Shepard SiegelJoseph A Kim
Apr 9, 2005·Journal of Applied Physiology·Niels P RiksenGerard A Rongen
Aug 22, 2001·American Journal of Physiology. Heart and Circulatory Physiology·C F NotariusJ S Floras

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiovascular Diseases: Risk Factors

Cardiovascular disease is a significant health concern. Risk factors include hypertension, obesity, dyslipidemia and smoking. Women who are postmenopausal are at an increased risk of heart disease. Here is the latest research for risk factors of cardiovascular disease.