Caffeine, alcohol, smoking, and the risk of incident epithelial ovarian cancer

Cancer
Shelley S TworogerSusan E Hankinson

Abstract

Smoking, caffeine, and alcohol intake are all potentially modifiable factors that have an unclear association with ovarian cancer risk. Therefore, the associations between these exposures and ovarian cancer risk were prospectively examined among 110,454 women in the Nurses' Health Study (NHS) for the smoking analyses and 80,253 women for the dietary analyses. Women completed biennial questionnaires assessing ovarian cancer risk factors beginning in 1976, with food frequency questionnaires administered every 2 to 4 years starting in 1980. For the smoking analyses, 737 confirmed cases of epithelial ovarian cancer were identified and for the dietary aims, 507 cases were identified through June 1, 2004. Compared with never-smokers, neither current nor past smoking was associated with ovarian cancer risk overall; however, both were associated with mucinous tumors (n = 69; rate ratio [RR], past = 2.02 [95% confidence interval (CI), 1.15-3.55]; RR, current = 2.22 [95% CI, 1.16-4.24]). A modest inverse association between caffeine intake and ovarian cancer risk was observed (RR, top vs bottom quintile = 0.80; 95% CI, 0.60-1.07 [P = .03]), which was strongest for women who had never used either oral contraceptives (RR = 0.65; 95% CI, 0....Continue Reading

References

Sep 1, 1992·Journal of Clinical Epidemiology·C La VecchiaM Fasoli
Jan 1, 1992·Nutrition and Cancer·C La VecchiaP Boyle
Jul 1, 1989·American Journal of Obstetrics and Gynecology·P HartgeH J Norris
May 1, 1986·American Journal of Epidemiology·M L GwinnG L Rubin
Jan 1, 1985·European Journal of Clinical Pharmacology·D R Abernethy, E L Todd
Aug 1, 1984·European Journal of Cancer & Clinical Oncology·A TzonouA Polychronopoulou
May 1, 1984·American Journal of Epidemiology·M J StampferC H Hennekens
May 15, 1984·International Journal of Cancer. Journal International Du Cancer·C La VecchiaG Tognoni
Oct 15, 1982·International Journal of Cancer. Journal International Du Cancer·P HartgeR Hoover
Dec 1, 1981·International Journal of Cancer. Journal International Du Cancer·D TrichopoulosA Polychronopoulou
Sep 15, 1995·International Journal of Cancer. Journal International Du Cancer·D PurdieB Susil
Nov 3, 1995·International Journal of Cancer. Journal International Du Cancer·A Nandakumar Srinivas
Sep 30, 1993·International Journal of Cancer. Journal International Du Cancer·A PolychronopoulouD Trichopoulos
Jul 15, 1996·American Journal of Epidemiology·W ZhengA R Folsom
Oct 1, 1996·American Journal of Epidemiology·R L Ferrini, E Barrett-Connor
Jan 12, 1999·American Journal of Epidemiology·L H KushiT A Sellers
Mar 20, 1999·American Journal of Epidemiology·L FensterS H Swan
Sep 3, 1999·Journal of Clinical Pharmacology·B G PollockK A Condifer
Sep 27, 2000·International Journal of Cancer. Journal International Du Cancer·H KuperD W Cramer
Jan 9, 2001·International Journal of Cancer. Journal International Du Cancer·P LagiouH O Adami
Mar 5, 2002·British Journal of Cancer·M ZhangA H Lee
Aug 16, 2002·American Journal of Epidemiology·Tomas RimanIngemar R Persson
Dec 20, 2002·Gastroenterology Clinics of North America·Edward Giovannucci
Jan 25, 2003·Current Opinion in Obstetrics & Gynecology·Cecile T M Brekelmans
May 9, 2003·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·P D TerryT E Rohan
Aug 20, 2003·Nutrition and Cancer·Marc T GoodmanTimothy A Donlon
Mar 5, 2004·Journal of the National Cancer Institute·Susanna C LarssonAlicja Wolk
Mar 16, 2004·Cancer Causes & Control : CCC·Leo J SchoutenPiet A van den Brandt
May 14, 2004·Cancer Causes & Control : CCC·Susan J JordanPenelope M Webb
Jun 9, 2004·International Journal of Cancer. Journal International Du Cancer·Sai Yi PanUNKNOWN Canadian Cancer Registries Epidemiology Research Group
Mar 18, 2005·The Journal of Obstetrics and Gynaecology Research·Yoshimitsu NiwaUNKNOWN JACC Study Group
Apr 2, 2005·Cancer Causes & Control : CCC·Linda E KelemenJames R Cerhan
Sep 21, 2005·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Susanna C Larsson, Alicja Wolk
Dec 14, 2005·Archives of Internal Medicine·Susanna C Larsson, Alicja Wolk
Feb 14, 2006·Molecular Nutrition & Food Research·Anna H Wu, Mimi C Yu
Feb 24, 2006·British Journal of Cancer·J M GenkingerS A Smith-Warner
Sep 29, 2006·Gynecologic Oncology·Susan J JordanPenelope M Webb
Dec 23, 2006·Cancer Causes & Control : CCC·Ellen T ChangPamela L Horn-Ross
Feb 13, 2007·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·J A BakerK B Moysich
Mar 3, 2007·Obstetrics and Gynecology·Susan J JordanPenelope M Webb
Mar 21, 2007·Toxicological Sciences : an Official Journal of the Society of Toxicology·Helen Pui Shan WongChi-Hin Cho
Jun 6, 2007·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Marie SoegaardSusanne K Kjaer

❮ Previous
Next ❯

Citations

Jan 12, 2011·European Journal of Clinical Pharmacology·Yao ChenHong-Hao Zhou
Aug 16, 2008·Cancer Causes & Control : CCC·Natalie A LuethKim Robien
Sep 25, 2010·Cancer Causes & Control : CCC·Sandra C JonesDonald C Iverson
Aug 3, 2013·Cancer Causes & Control : CCC·Milan S GeybelsJanet L Stanford
Mar 25, 2011·Critical Reviews in Food Science and Nutrition·Masood Sadiq Butt, M Tauseef Sultan
Nov 17, 2009·American Journal of Epidemiology·Margaret A GatesShelley S Tworoger
Feb 22, 2012·Clinical Obstetrics and Gynecology·Jessica Hunn, Gustavo C Rodriguez
Aug 10, 2010·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Kathryn M WilsonWalter C Willett
Nov 24, 2011·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Youjin JeEdward Giovannucci
Jan 24, 2012·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Kathryn L TerryDaniel W Cramer
Aug 2, 2012·International Journal of Environmental Research and Public Health·Reuben ThomasLuoping Zhang
Jan 13, 2012·The American Journal of Clinical Nutrition·Karen C SchliepJean Wactawski-Wende
Oct 23, 2008·Cancer Causes & Control : CCC·Joanne KotsopoulosShelley S Tworoger
Mar 5, 2013·Cancer Causes & Control : CCC·Mette T FaberUNKNOWN Ovarian Cancer Association Consortium
Feb 19, 2013·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Jing XieShelley S Tworoger
Nov 21, 2009·European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP)·Anette HjartåkerElisabete Weiderpass
Oct 5, 2010·Nutrition·Michael J Glade
Oct 7, 2008·Cancer Letters·André Nkondjock
Jun 17, 2011·International Journal of Cancer. Journal International Du Cancer·Inger T GramRudolf Kaaks
Oct 1, 2011·International Journal of Cancer. Journal International Du Cancer·Hannah P YangNicolas Wentzensen
Aug 9, 2011·Molecular Nutrition & Food Research·Irina I KolevaIvonne M C M Rietjens
Jul 2, 2009·International Journal of Cancer. Journal International Du Cancer·Kim N DanforthSusan E Hankinson
Jul 9, 2009·International Journal of Cancer. Journal International Du Cancer·Joanne KotsopoulosShelley S Tworoger
Dec 6, 2014·Journal of Ovarian Research·Jing XieShelley S Tworoger
Aug 21, 2015·British Journal of Cancer·Mia HashibeCarlo La Vecchia
Aug 2, 2011·Gynecologic Oncology·Michael BodmerChristoph R Meier
Mar 28, 2012·Gynecologic Oncology·Matteo RotaVincenzo Bagnardi
Jul 9, 2010·Journal of Gynecologic Oncology·Hee Seung KimSoon-Beom Kang
Aug 7, 2012·The Lancet Oncology·UNKNOWN Collaborative Group on Epidemiological Studies of Ovarian CancerR Peto
Sep 27, 2016·Scientific Reports·Anqiang WangHaitao Zhao
Dec 14, 2016·British Journal of Cancer·Idlir LicajInger Torhild Gram
Dec 17, 2017·Cancer Science·Tomotaka UgaiUNKNOWN Ovarian Cancer Association Consortium
Oct 26, 2018·Environmental and Molecular Mutagenesis·Ulrike LudererFrancesco Marchetti
Mar 24, 2012·The American Journal of Clinical Nutrition·Marieke G M BraemPetra H M Peeters
Jun 1, 2012·The American Journal of Clinical Nutrition·Eline M RodenburgLoes E Visser
Jul 10, 2019·The Journal of Clinical Endocrinology and Metabolism·Asma Salari-MoghaddamAhmad Esmaillzadeh
Jun 2, 2018·Oncotarget·Alia GhoneumNeveen Said

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Cancer Causes & Control : CCC
Susan J JordanPenelope M Webb
International Journal of Cancer. Journal International Du Cancer
H KuperD W Cramer
International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society
J A BakerK B Moysich
Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology
Yoon Ju SongMary Anne Rossing
© 2021 Meta ULC. All rights reserved