Abstract
An experiment was carried out to determine whether caffeinated and decaffeinated coffee removed the malaise (reduced alertness, slower psychomotor performance) associated with having a common cold. One hundred volunteers were tested when healthy and 46 returned to the laboratory when they developed colds. Those subjects who remained healthy were then recalled as a control group. On the second visit subjects carried out two sessions, one pre-drink and another an hour after the drink. Subjects were randomly assigned to one of the following three conditions, caffeinated coffee (1.5 mg/kg caffeine/body weight), decaffeinated coffee or fruit juice. Subjects with colds reported decreased alertness and were slower at performing psychomotor tasks. Caffeine increased the alertness and performance of the colds subjects to the same level as the healthy group and decaffeinated coffee also led to an improvement. These results suggest that drugs which increase alertness can remove the malaise associated with the common cold, and that increased stimulation of the sensory afferent nerves may also be beneficial.
References
Dec 1, 1976·The British Journal of Medical Psychology·M HerbertC Doré
Apr 12, 1990·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·A P Smith
Jan 1, 1990·Neuropsychobiology·A P SmithP Leathwood
Jan 1, 1990·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·G I BarrowD A Tyrrell
Jan 1, 1989·Neuropsychobiology·A P SmithS Trickett
Feb 1, 1988·Psychological Medicine·A P SmithJ S Willman
Jan 1, 1987·Neuropsychobiology·A P SmithJ S Willman
May 1, 1987·British Journal of Psychology·A P SmithJ S Willman
Jan 1, 1994·Psychopharmacology·M M LoristA Kok
Jan 1, 1993·Neuropsychobiology·A P SmithM Thomas
Jan 1, 1993·Journal of Personality and Social Psychology·S CohenA P Smith
Mar 20, 1993·BMJ : British Medical Journal·A P SmithK G Nicholson
Mar 28, 1996·Nature·A Smith, D Nutt
Mar 1, 1996·Physiology & Behavior·S Hall, A Smith
Jan 1, 1991·Journal of Psychopharmacology·A P SmithR Wenham
Jan 1, 1995·Journal of Psychopharmacology·A P SmithK Perry
Citations
Feb 5, 2013·Psychopharmacology·Andrew P Smith
Aug 27, 1999·Physiology & Behavior·A P SmithJ Gallagher
Sep 3, 2002·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·A Smith
Dec 17, 1998·Psychoneuroendocrinology·A SmithK Nicholson
May 10, 2005·The British Journal of Nutrition·Andrew P Smith
Jul 21, 2000·Ergonomics·A SmithH Whitney
Oct 3, 2000·Ergonomics·A SmithH Whitney
Jul 5, 2012·BMJ Open·Andrew Paul Smith, Samantha Jamson
Nov 30, 2013·Psychopharmacology·Andrew P Smith, David J Nutt
Jun 8, 2012·Stress and Health : Journal of the International Society for the Investigation of Stress·Andrew P Smith, Charlotte Boden
Apr 24, 2013·Psychoneuroendocrinology·Andrew P Smith
Oct 2, 2012·Psychoneuroendocrinology·Andrew P Smith
Nov 8, 2005·Journal of Psychopharmacology·Andrew SmithGary Christopher
Sep 4, 1999·Journal of Psychopharmacology·A SmithD J Nutt
Sep 30, 2003·Journal of Psychopharmacology·Andrew SmithDavid J Nutt
Mar 1, 2012·Behavioral Sciences·Andrew P Smith
Jun 19, 2018·Frontiers in Pharmacology·Laura López-CruzMercè Correa