PMID: 11336759May 5, 2001Paper

Caffeine-induced hypokalemic paralysis in pregnancy

Obstetrics and Gynecology
C C Appel, T D Myles

Abstract

Excessive ingestion of caffeine can induce hypokalemia, which affects the neuromuscular system and can lead to paralysis. A 24-year-old woman, gravida 3, para 2-0-0-2 at 33 weeks' gestation presented with muscular paralysis and hypokalemia secondary to drinking 6 to 7 L of cola per day with little other oral intake. After potassium replacement and stopping caffeine ingestion, the symptoms resolved quickly. The physiologic changes of pregnancy might potentiate the effect of caffeine on serum potassium concentration.

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Citations

Mar 11, 2010·Clinical Journal of Sport Medicine : Official Journal of the Canadian Academy of Sport Medicine·Igino RigatoFulvio Kette
Jun 6, 2009·International Journal of Clinical Practice·V TsimihodimosM Elisaf
Sep 23, 2009·International Journal of Clinical Practice·C Berry
Jan 1, 2010·Clinical Medicine Insights. Case Reports·Yutaka Tajima
May 13, 2014·Evidence-based Complementary and Alternative Medicine : ECAM·Su Jin SongTaesun Park
Jul 31, 2012·Neurologic Clinics·Amanda C Guidon, E Wayne Massey
Oct 1, 2008·British Journal of Clinical Pharmacology·L R H de WijkersloothA K M Bartelink
Jan 22, 2011·Obstetrics and Gynecology·Thomas D Myles
Nov 29, 2012·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·Rajeev Sharma, Helena A Guber
Jun 20, 2019·The Journal of Obstetrics and Gynaecology Research·Anna Frappaolo, Mary Vadnais
May 31, 2011·Current Sports Medicine Reports·E Randy Eichner
Dec 24, 2018·Obstetric Medicine·Stephanie Teasdale, Adam Morton
Aug 19, 2007·European Journal of Internal Medicine·Arsenio PompeoNicola Genovesi

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