PMID: 9663851Jul 15, 1998Paper

Calbindin-D 28 kD and parvalbumin in the horizontal cells of rat retina during development

Current Eye Research
M OguniK Kato

Abstract

Calbindin-D 28K (CaD) and parvalbumin (PV) are calcium-binding proteins thought to act as an intraneural calcium ion buffering system in the central nervous system. We previously reported that PV appears at birth in some cells in the outer portion of the nuclear layer of the retina that can differentiate into horizontal cells. CaD is also distributed in horizontal cells; however, it is not clear at which developmental stage CaD appears. The development of horizontal cells and the distribution of CaD and PV was examined ultrastructurally and immunohistochemically in rat retinas from birth (P0) to postnatal day 50 (P50). Our ultrastructural data showed clear differentiation of horizontal cells from other retinal cells in the early postnatal days. These cells became nearly mature around P10 to P12. PV appeared in the outer nuclear layer at birth (P0) and, by P7, was observed in the ganglion cell layer, amacrine cells, and horizontal cells. CaD-immunoreactive cells, however, were not seen in any portions of the retina until P7. At P10, CaD-immunoreactivity was faintly observed in horizontal cells, and its immunoreactivity gradually increased in the horizontal cells from P10 to P15 when the eyes of the rats opened. CaD was not found...Continue Reading

References

Apr 1, 1992·Experimental Eye Research·R UesugiS U Kim
Sep 2, 1991·Biochimica Et Biophysica Acta·Y InagumaK Kato
Jul 1, 1990·Visual Neuroscience·B PasteelsR Pochet
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Apr 1, 1981·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·S M HsuH Fanger
Mar 1, 1995·Experimental Eye Research·E BastianelliR Pochet

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Citations

Aug 15, 2014·Experimental Neurology·Lais Takata WalterAlexandre Hiroaki Kihara
Nov 26, 2015·Experimental Eye Research·Chris Joon Ho HongAlexander K Ball
Mar 31, 2000·Developmental Dynamics : an Official Publication of the American Association of Anatomists·W LiuM Xiang
Jan 13, 2001·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·A NakazawaS Higuchi

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