PMID: 9174253May 20, 1997Paper

Calbindin-D28k is regulated by adrenal steroids in hypothalamic tissue during prenatal development

Brain Research. Developmental Brain Research
E D LephartD R Ladle

Abstract

Regulation of calbindin-D28k (CALB) in the medial basal hypothalamus (MBH) from male and female fetuses was examined by Western analysis. Control fetal males displayed significantly higher MBH CALB levels compared to females at gestational day 20. Whereas, in general, the lowest CALB levels were recorded in male and female fetuses from long-term prenatally stressed or fetuses from adrenalectomized pregnant rats. These data indicate that corticosterone regulates MBH CALB expression during prenatal development and CALB may be implicated in modulating the sexual differentiation of neural structures within the MBH during perinatal development.

References

Jan 1, 1992·Experimental Gerontology·M P Mattson
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Jan 1, 1987·Anatomy and Embryology·S EnderlinM R Celio
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Citations

Sep 3, 2002·Neuroscience and Biobehavioral Reviews·Ora Kofman
Aug 17, 2001·Brain Research. Developmental Brain Research·E B StuartE D Lephart
May 13, 1999·Brain Research. Developmental Brain Research·H TaylorE D Lephart
Jul 14, 1998·Neurobiology of Aging·E D LephartM A Watson
Jun 14, 2006·Behavioral Neuroscience·Christie BurtonAlison S Fleming
Aug 17, 2010·Epilepsy & Behavior : E&B·Tiago Gurgel do ValeDébora Amado
Apr 12, 2016·Nihon yakurigaku zasshi. Folia pharmacologica Japonica·Kazuya MiyagawaHiroshi Takeda
May 12, 2010·Frontiers in Neuroendocrinology·P J BonthuisE F Rissman

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