Calbindin-immunopositive cells are cholinergic interneurons in the myenteric plexus of rabbit ileum

Cell and Tissue Research
V Dénes, R Gábriel

Abstract

The 28-kDa calcium-binding protein (calbindin) is a widely studied neuronal marker in the enteric nervous system of numerous species. Calbindin has previously been detected in myenteric neurons of rabbit ileum in which 3% of all myenteric neurons are calbindin-immunopositive. We have studied the detailed morphology and chemical coding of calbindin-immunopositive neurons in this segment of the gut. We have found calbindin immunoreactivity in both strongly and weakly stained neurons. Of these, the strongly immunoreactive neurons belong to the Dogiel type I category. These neurons project only to other ganglia and primary strands of the plexus and their processes never run to the muscle or mucosal layers. The neurons within this group are 29.5+/-6.6 microm in length and 14.7+/-3.8 microm in width. The second smaller group of immunoreactive cells (27%) label faintly and have different morphological properties. They are characterized by their round medium-sized cell bodies (long axis: 24.4+/-5.2 microm; short axis: 15.5+/-2.9 microm) and do not exhibit immunoreactivity either in their dendrites or in their axonal processes. Double-label studies show that all calbindin-immunopositive neurons lack immunoreactivity for nitric oxide syn...Continue Reading

References

Jan 1, 1988·Annals of the New York Academy of Sciences·J R Grider, G M Makhlouf
Mar 1, 1988·Cell and Tissue Research·A RésiboisR Pochet
Jan 1, 1988·Baillière's Clinical Gastroenterology·G S Taylor, R A Bywater
May 1, 1994·Cell and Tissue Research·K McConalogueJ B Furness
Feb 1, 1993·Cell and Tissue Research·C AndressenM R Celio
Feb 14, 1998·Progress in Neurobiology·J B FurnessJ C Bornstein
Sep 8, 1999·European Journal of Morphology·W B CornelissenJ P Timmermans
Mar 12, 2003·The Anatomical Record. Part A, Discoveries in Molecular, Cellular, and Evolutionary Biology·Viktória DénesRobert Gábriel
May 6, 1966·Science·R H Wasserman, A N Taylor

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Citations

Aug 24, 2013·Research in Veterinary Science·J SadeghinezhadR Chiocchetti
Aug 3, 2010·Autonomic Neuroscience : Basic & Clinical·Catharina Olsson
Jul 29, 2008·Journal of Anatomy·Juliane MünnichHelga Pfannkuche
Sep 5, 2012·Anatomia, histologia, embryologia·J SadeghinezhadR Chiocchetti
Sep 21, 2010·The Journal of Comparative Neurology·Leen UyttebroekLuc Van Nassauw
Jun 8, 2010·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·A di GiancamilloC Domeneghini
Apr 8, 2006·Neuroscience Letters·Hirofumi KuramotoRyozo Kuwano
Nov 1, 2016·Journal of Molecular Neuroscience : MN·Joanna WojtkiewiczSławomir Gonkowski

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