Calcifications of lobular carcinoma in situ of the breast: radiologic-pathologic correlation

AJR. American Journal of Roentgenology
D Georgian-Smith, T J Lawton

Abstract

Because lobular carcinoma in situ is thought to be an incidental finding at breast pathology, the finding of lobular carcinoma in situ at core biopsy poses a diagnostic dilemma of radiologic-pathologic concordance. The purpose of this article is to describe the radiologic-pathologic correlation of calcifications associated with lobular carcinoma in situ of the breast. Between July 1999 and July 2000, seven excisional biopsies resulted in findings of lobular carcinoma in situ of mammographic calcifications. The radiographic features of the calcifications were characterized by the Breast Imaging Reporting and Data System lexicon, and pathologic features were reviewed. Two forms of lobular carcinoma in situ were associated with calcifications: the classic form with small, uniform cells, and the pleomorphic form with larger cells frequently associated with central necrosis. On mammography, all calcifications were clustered, punctate, high density, and smaller than or equal to 0.5 mm, although mammographically visible calcifications found in the pleomorphic type tended to be larger and more dense. Additionally, infiltrating lobular carcinoma was found after surgical excision in two (40%) of five patients with pleomorphic lobular car...Continue Reading

References

Jan 1, 1989·AJR. American Journal of Roentgenology·D B Kopans, C A Swann
Dec 1, 1989·AJR. American Journal of Roentgenology·M J HomerD J Marchant
Feb 11, 1998·Journal of Surgical Oncology·T NemotoR L Bauer
Aug 3, 1999·AJR. American Journal of Roentgenology·L LibermanD D Dershaw
May 2, 2000·AJR. American Journal of Roentgenology·H E Reynolds
Feb 15, 2001·The American Journal of Surgical Pathology·T W JacobsS J Schnitt

❮ Previous
Next ❯

Citations

Aug 10, 2006·Der Pathologe·H P SinnS Aulmann
Apr 5, 2008·Virchows Archiv : an International Journal of Pathology·S MenonA H S Lee
May 22, 2008·Pathology Oncology Research : POR·Simonetta Bianchi, Vania Vezzosi
Jun 20, 2008·European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP)·Nelia Afonso, David Bouwman
Aug 25, 2009·The American Journal of Surgical Pathology·Yunn-Yi ChenFrederic M Waldman
Feb 22, 2008·AJR. American Journal of Roentgenology·Rachel F BremShane Wasden
Oct 24, 2013·AJR. American Journal of Roentgenology·Colleen H NealMark A Helvie
May 24, 2005·AJR. American Journal of Roentgenology·Lauren F SteinRachel F Brem
Jun 3, 2014·Surgical Oncology Clinics of North America·Tari A King, Jorge S Reis-Filho
Aug 21, 2013·Archivum Immunologiae Et Therapiae Experimentalis·Eva VlugPatrick W B Derksen
Feb 18, 2011·The British Journal of Radiology·X ZhangS Taizo
Jan 24, 2012·AJR. American Journal of Roentgenology·Dianne Georgian-Smith, Thomas J Lawton
Jan 24, 2012·AJR. American Journal of Roentgenology·Stamatia V DestounisWende Logan Young
Jan 24, 2012·AJR. American Journal of Roentgenology·Savitri KrishnamurthyWei T Yang
Sep 22, 2012·AJR. American Journal of Roentgenology·Bethany NiellElizabeth Rafferty
Apr 3, 2010·Pathology, Research and Practice·Marilin RosaShahla Masood
Jul 16, 2008·The Breast : Official Journal of the European Society of Mastology·Viviana LonderoMassimo Bazzocchi
Feb 5, 2005·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Bruno CutuliEliane Mery
May 27, 2014·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·A S WallaceP S Dale
Jul 2, 2016·Expert Review of Anticancer Therapy·Ludivine DionVincent Lavoué
Mar 24, 2010·Seminars in Diagnostic Pathology·Emad A Rakha, Ian O Ellis
Oct 27, 2009·Journal de gynécologie, obstétrique et biologie de la reproduction·V LavouéJ Levêque
Oct 9, 2007·Seminars in Roentgenology·Liane E Philpotts
Jul 16, 2002·Radiologic Clinics of North America·Laura Liberman
Jul 17, 2007·The Breast : Official Journal of the European Society of Mastology·Vincent LavouéJean Levêque
Aug 2, 2003·International Journal of Surgical Pathology·Sami Shousha
Aug 13, 2014·World Journal of Clinical Oncology·Andrew PieriNigel Bundred
Jul 29, 2008·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Helena HwangBarbara Susnik
May 14, 2010·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Frances P O'Malley
Jul 9, 2004·Cancer·Grazia ArpinoRichard M Elledge
Jun 13, 2018·AJR. American Journal of Roentgenology·Julia L SavageMark A Helvie
Oct 26, 2006·The American Journal of Surgical Pathology·Oluwole FadareFattaneh A Tavassoli
Aug 13, 2010·The Breast Journal·Ramachandran Venkitaraman
Feb 27, 2003·The American Journal of Surgical Pathology·Giovanna Maria CrisiAndrew Ricci

❮ Previous
Next ❯

Related Concepts

Related Feeds

Carcinoma, Ductal

Ductal carcinoma is a malignant neoplasm involving the ductal systems of any of a number of organs, such as the mammary glands, pancreas, prostate or lacrimal gland. Discover the latest research on ductal carcinoma here.

Carcinoma, Lobular

Lobular carcinoma is an invasive type of breast cancer in which lobules, areas of the breast that produce milk, undergo malignant transformation. Here is the latest research.