Calcified Pulmonary Nodules Identified in a 350-Year-Old-Joseon Mummy: the First Report on Ancient Pulmonary Tuberculosis from Archaeologically Obtained Pre-modern Korean Samples

Journal of Korean Medical Science
Yi-Suk KimDong Hoon Shin

Abstract

We found calcified pulmonary nodules in a middle-aged female mummy discovered from 350-yr-old Joseon tomb of Korea. In the CT scan, we found six radiopaque nodules in right lung, through the levels of thoracic vertebrae 1 to 6. We also found presumptive pleural adhesions in right thoracic cavity of CT images. We re-confirmed radiological findings by our post-factum dissection on the same mummy. By the differential diagnosis, we speculate that the radiopaque calcification nodules and associated pleural adhesion could have been caused by tuberculosis. This is the first-ever report on the pulmonary tuberculosis identified in archaeologically obtained, pre-modern Korean samples.

References

Jul 1, 1979·Seminars in Roentgenology·P E Palmer
Jun 1, 1995·AJR. American Journal of Roentgenology·K S Lee, J G Im
Nov 1, 1994·Radiographics : a Review Publication of the Radiological Society of North America, Inc·K BrownD A Young
Nov 1, 1993·Radiographics : a Review Publication of the Radiological Society of North America, Inc·B A UrbanR H Hruban
May 1, 1996·Radiology·J W Gurney, D J Conces
Sep 1, 2004·The Lancet Infectious Diseases·Helen D DonoghueAlbert R Zink
Jun 29, 2010·Annals of Thoracic Medicine·Ali Nawaz KhanShyam Sunder Koteyar
Feb 28, 2014·Proceedings. Biological Sciences·Romy MüllerTerence A Brown

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