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Calcitonin gene-related peptide and substance P contribute to reduced blood pressure in sympathectomized rats

American Journal of Physiology. Heart and Circulatory Physiology

Sep 1, 2005

Scott C SupowitDonald J DiPette

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Abstract

CGRP and substance P (SP) are produced in dorsal root ganglia (DRG) sensory neurons and modulate vascular tone. Sympathetic and sensory nerves compete for NGF, a potent stimulator of CGRP and SP, and it has been suggested that sympathetic hyperinnervation in spontaneously hypertensive r...read more

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Blood Pressure
Entire Spleen
Cerebral Ventricles
Sensory Receptor Cells
Nervousness
Both Cardiac Atria
S100A12 protein, human
Blood Vessel
Norepinephrine
Ganglia, Spinal
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Calcitonin gene-related peptide and substance P contribute to reduced blood pressure in sympathectomized rats

American Journal of Physiology. Heart and Circulatory Physiology

Sep 1, 2005

Scott C SupowitDonald J DiPette

PMID: 15879482

DOI: 10.1152/ajpheart.00973.2004

Abstract

CGRP and substance P (SP) are produced in dorsal root ganglia (DRG) sensory neurons and modulate vascular tone. Sympathetic and sensory nerves compete for NGF, a potent stimulator of CGRP and SP, and it has been suggested that sympathetic hyperinnervation in spontaneously hypertensive r...read more

Mentioned in this Paper

Blood Pressure
Entire Spleen
Cerebral Ventricles
Sensory Receptor Cells
Nervousness

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Paper Details
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