Calcium absorption and bone mineral density in celiacs after long term treatment with gluten-free diet and adequate calcium intake

Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
M PazianasJ D Maxwell

Abstract

Calcium malabsorption, hypocalcemia and skeletal demineralization are well-recognized features of untreated celiac disease. This study investigates calcium absorption and bone mineral density (BMD) after a prolonged, over 4 years, treatment with a gluten-free diet. Twenty-four adult females with treated celiac disease and twenty age- and sex-matched control subjects were studied. Mean body mass index (MBI), energy intake, serum calcium, and serum 25(OH)D concentrations in treated celiacs did not differ from controls. However, while both dietary calcium and protein intake were significantly higher in celiacs (P<0.012), fractional calcium absorption was lower (mean percentage+/-SD; treated 39.8+/-12 versus controls 52.3+/-10, P<0.001). Thus, after adjusting for calcium intake, the estimated amount of calcium absorbed daily was similar in both groups. Whole body, spine and trochanter BMD were significantly lower in treated celiac patients compared with controls (P<0.05). There were significant inverse correlations between: serum parathyroid hormone (PTH) and femoral neck or total body BMD (P<0.01), PTH and duration of gluten-free diet (P=0.05), and fractional calcium absorption and alkaline phosphatase (P=0.022). Increased calcium...Continue Reading

References

Feb 1, 1978·The American Journal of Digestive Diseases·M S SchoenP R Holt
Dec 12, 1991·The New England Journal of Medicine·J S Trier
Jun 1, 1988·Annals of Internal Medicine·R P Heaney, R R Recker
Oct 1, 1985·Annals of Internal Medicine·R P Heaney, R R Recker
Sep 1, 1969·The Journal of Clinical Investigation·R H WenselW Volwiler
Apr 30, 1983·Lancet·D R Fraser
Jul 1, 1995·Gastroenterology·G R CorazzaG Gasbarrini
May 1, 1995·Gut·X A McFarlaneD A Robertson
May 1, 1994·Scandinavian Journal of Gastroenterology·T ValdimarssonM Ström
Feb 1, 1993·The American Journal of Clinical Nutrition·S MoraG Chiumello
Mar 1, 1996·Gut·T ValdimarssonM Ström
Feb 18, 1999·The American Journal of Gastroenterology·S MoraG Chiumello
Mar 11, 1999·Bone·T KemppainenM Uusitupa
Mar 20, 1999·The Journal of Biological Chemistry·J G HoenderopR J Bindels
Jan 19, 2000·The American Journal of Gastroenterology·H VasquezJ C Bai
May 9, 2000·The American Journal of Clinical Nutrition·R P HeaneyJ Bierman
Jun 13, 2001·American Journal of Physiology. Cell Physiology·B M Slepchenko, F Bronner
Nov 24, 2001·Cell·Y GongUNKNOWN Osteoporosis-Pseudoglioma Syndrome Collaborative Group
Aug 31, 2002·Endocrine Reviews·Pekka CollinJorma Salmi
Jan 31, 2003·Gastrointestinal Endoscopy·Susie K LeePeter H R Green
Apr 4, 2003·Journal of the American College of Nutrition·Robert P HeaneyAdrianne Bendich
Dec 1, 1956·A.M.A. Archives of Internal Medicine·J L JUERGENSE E WOLLAEGER

❮ Previous
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Citations

Feb 5, 2005·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·Michael W DavieG D Summers
Oct 9, 2009·The New England Journal of Medicine·Philip L RichesStuart H Ralston
Feb 28, 2008·Current Opinion in Gastroenterology·Helen M PappaRichard J Grand
Jun 28, 2012·Gastroenterology Research and Practice·Tiziana LarussaFrancesco Luzza
Apr 25, 2012·World Journal of Gastroenterology : WJG·Tiziana LarussaFrancesco Luzza
Jun 6, 2013·European Journal of Endocrinology·Cristina Eller-VainicherIacopo Chiodini
Feb 28, 2014·The Proceedings of the Nutrition Society·M ClarkeH McNulty
Sep 30, 2009·Nutrition Reviews·Vanessa D CaprilesJosé Alfredo G Arêas
Jan 16, 2007·Internal and Emergency Medicine·Davide LazzariniGiorgio Ioli
May 10, 2011·Internal and Emergency Medicine·Giuseppe FanciulliGiuseppe Delitala
Apr 18, 2008·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·M-L Bianchi, M T Bardella
Nov 30, 2005·The Proceedings of the Nutrition Society·Norma McGough, John H Cummings
Sep 22, 2011·Current Osteoporosis Reports·Manasi AgrawalMone Zaidi
Aug 11, 2012·Endocrinology and Metabolism Clinics of North America·Ronald D Emkey, Gregory R Emkey
Feb 11, 2012·Endocrinología y nutrición : órgano de la Sociedad Española de Endocrinología y Nutrición·Rebeca Reyes GarcíaUNKNOWN Grupo de Metabolismo Mineral de la Sociedad Espa˜nola de Endocrinología y Nutrición
Feb 4, 2016·Revista Española De Enfermedades Digestivas : Organo Oficial De La Sociedad Española De Patología Digestiva·Lorete M S KotzeRenato Nisihara
May 3, 2007·Gastroenterology Clinics of North America·Susan E Williams, Douglas L Seidner
Aug 2, 2008·Alimentary Pharmacology & Therapeutics·M L HainesP R Gibson
Jun 7, 2008·The Journal of Pediatrics·Chiara ZanchiAlessandro Ventura
May 12, 2005·Archives de pédiatrie : organe officiel de la Sociéte française de pédiatrie·R Cimaz, S Guez
Nov 8, 2014·TheScientificWorldJournal·Stefano PantaleoniMarco Astegiano
Jun 21, 2015·Calcified Tissue International·Ana RealPhilip L Riches
Sep 26, 2016·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·Prashant Singh, John J Garber
Mar 6, 2013·Annals of Saudi Medicine·Asaad AssiriWael El Matary
Oct 22, 2015·Arquivos De Gastroenterologia·Joyce Timmermans Pires da SilvaLorete Maria da Silva Kotze
Feb 17, 2018·Public Health Reviews·M FiscalettiC F Munns
Aug 1, 2009·Journal of Pediatric Gastroenterology and Nutrition·Justine TurnerDiana Mager
Apr 20, 2018·Journal of Clinical Gastroenterology·Michele Di StefanoAntonio Di Sabatino
Feb 24, 2017·Foods·Urszula Krupa-Kozak, Natalia Drabińska
Dec 6, 2017·Calcified Tissue International·Barbara Hauser, Ulrike Harre
Aug 17, 2020·Journal of Pediatric Gastroenterology and Nutrition·Chiara TortoraFrancesca Rossi
Oct 24, 2020·Journal of Pediatric Gastroenterology and Nutrition·Chiara TortoraFrancesca Rossi
Jul 6, 2010·Archives of Biochemistry and Biophysics·Maria Luisa Bianchi
Aug 5, 2008·Pediatrics·Madhusmita MisraUNKNOWN Drug and Therapeutics Committee of the Lawson Wilkins Pediatric Endocrine Society

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