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Calcium antagonists inhibit positive chronotropic responses to alpha 1-adrenoceptor activation in rat isolated atria

European Journal of Pharmacology

Jan 13, 1987

L H TungW J Louis

Abstract

Positive chronotropic responses of rat isolated atria to phenylephrine were reduced by propranolol (0.3 microM) and the residual response was further depressed by the selective alpha 1-adrenoceptor antagonist prazosin (1 nM) but not yohimbine (10 nM), confirming that a component of the ...read more

Mentioned in this Paper

Calcium Measurement
Depressed - Symptom
Antagonist Muscle Action
Pulse Rate
Muscle, Smooth, Vascular
Nifedipine
Aorta
Phenylephrine
Phenylephrine Hydrochloride
Prazosin
Paper Details
References
  • References12
  • Citations7
12

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Calcium antagonists inhibit positive chronotropic responses to alpha 1-adrenoceptor activation in rat isolated atria

European Journal of Pharmacology

Jan 13, 1987

L H TungW J Louis

PMID: 2434348

DOI: 10.1016/0014-2999(87)90148-8

Abstract

Positive chronotropic responses of rat isolated atria to phenylephrine were reduced by propranolol (0.3 microM) and the residual response was further depressed by the selective alpha 1-adrenoceptor antagonist prazosin (1 nM) but not yohimbine (10 nM), confirming that a component of the ...read more

Mentioned in this Paper

Calcium Measurement
Depressed - Symptom
Antagonist Muscle Action
Pulse Rate
Muscle, Smooth, Vascular
Nifedipine
Aorta
Phenylephrine
Phenylephrine Hydrochloride
Prazosin

Similar Papers Found In These Feeds

Related Papers

Paper Details
References
  • References12
  • Citations7
12
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