Calcium-binding proteins immunoreactivity in the human subcortical and cortical visual structures

Visual Neuroscience
G Leuba, K Saini

Abstract

The distribution of neurons and fibers immunoreactive (ir) to the three calcium-binding proteins parvalbumin (PV), calbindin D-28k (CB), and calretinin (CR) was studied in the human lateral geniculate nucleus (LGN), lateral inferior pulvinar, and optic radiation, and related to that in the visual cortex. In the LGN, PV, CR, and CB immunoreactivity was present in all laminae, slightly stronger in the magnocellular than in the parvocellular laminae for CB and CR. PV-ir puncta, representing transversally cut axons, and CR-ir fibers were revealed within the laminae and interlaminar zones, and just beyond the outer border of lamina 6 in the geniculate capsule. In the optic radiation both PV- and CR-immunoreactive neurons, puncta, and fibers were present. CB immunoreactivity was revealed in neurons of all laminae of the lateral geniculate nucleus, including S lamina and interlaminar zones. There were hardly any CB-ir puncta or fibers in the laminae, interlaminar zones, geniculate capsule, or optic radiation. In the lateral inferior pulvinar, immunoreactive neurons for the three calcium-binding proteins were present in smaller number than in the LGN, as well as PV-ir puncta and CR-ir fibers within the nucleus and in the pulvinar capsu...Continue Reading

References

Jul 1, 1992·Trends in Neurosciences·C W Heizmann, K Braun
Aug 1, 1992·Trends in Neurosciences·K G BaimbridgeJ H Rogers
Sep 15, 1992·The Journal of Comparative Neurology·R J MorecraftM M Mesulam
May 1, 1990·The Journal of Comparative Neurology·T P MaJ A Rafols
Feb 8, 1991·The Journal of Comparative Neurology·D M Jacobowitz, L Winsky
Jul 1, 1990·Visual Neuroscience·B PasteelsR Pochet
Apr 1, 1990·Proceedings of the National Academy of Sciences of the United States of America·S HockfieldS Zaremba
Nov 15, 1990·The Journal of Comparative Neurology·I BlümckeM R Celio
Oct 15, 1990·The Journal of Comparative Neurology·S Hockfield, M Sur
Jul 1, 1994·Trends in Neurosciences·V A Casagrande
May 29, 1995·The Journal of Comparative Neurology·J K Johnson, V A Casagrande
Nov 1, 1994·The Journal of Comparative Neurology·M J MustariF R Robinson
Feb 15, 1993·Proceedings of the National Academy of Sciences of the United States of America·I T DiamondD Schmechel
May 1, 1989·The European Journal of Neuroscience·E. G. Jones, S. H. C. Hendry

❮ Previous
Next ❯

Citations

Jun 22, 2000·The Anatomical Record·J González-SorianoP Martínez-Sainz
Jan 25, 2003·The European Journal of Neuroscience·Oriana ChiryStephanie Clarke
Mar 1, 2007·Acta Histochemica Et Cytochemica·Jea-Young LeeChang-Jin Jeon
Mar 20, 2008·Zoological Science·Jea-Young LeeChang-Jin Jeon
Dec 31, 1997·The Journal of Comparative Neurology·A MorelD Jeanmonod
Oct 2, 2002·The Journal of Comparative Neurology·Mary BehanM Alex Meredith
Jan 27, 2005·Experimental Brain Research·Sébastien DesgentMaurice Ptito
Jun 10, 2005·Journal of Neurophysiology·Keith A Schneider, Sabine Kastner
Apr 17, 2018·The Journal of Comparative Neurology·Mary K L Baldwin, Leah Krubitzer
May 22, 2018·Frontiers in Neural Circuits·Claudio A VillalobosMichele A Basso
Jul 30, 2021·Neuroscience Bulletin·Yingbei QiZhong Chen

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.