PMID: 6973762Jun 1, 1981Paper

Calcium-binding sites on sensory processes in vertebrate hair cells

Proceedings of the National Academy of Sciences of the United States of America
D T MoranD L Asher

Abstract

Vertebrate lateral line and vestibular systems center their function on highly mechanosensitive hair cells. Each hair cell is equipped with one kinocilium (which resembles a motile cilium) and 50-100 actin-containing stereocilia (which resemble microvilli) at the site of stimulus reception. This report describes electron-microscopic localization of calcium-binding sites on the sensory processes of vertebrate hair cells. Using the Oschman-Wall technique for calcium localization [Oschman, J. L. & Wall, B. J. (1972) J. Cell Biol. 55, 58-73] together with electron-probe x-ray microanalysis of thin sections, we observed: (i) calcium- and iron-containing deposits in the region of the ciliary necklace in goldfish lateral line hair cells, (ii) calcium deposits upon the surface of stereocilia of hair cells of the bullfrog inner ear, and (iii) calcium deposits upon stereocilia of hair cells of the guinea pig vestibular system.

References

Oct 25, 1979·Nature·D P Corey, A J Hudspeth
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Citations

Jul 10, 2007·Journal of the Association for Research in Otolaryngology : JARO·Mirna MustaphaSally A Camper
Jan 1, 1986·Hearing Research·D J Lim
Jan 1, 1986·Hearing Research·M Anniko, R Wróblewski
Jan 1, 1987·Hearing Research·R RomandN Giry
Aug 1, 1988·Hearing Research·K Ikeda, T Morizono
Jan 1, 2011·Journal of Functional Biomaterials·Keerthana DevarajanMichael S Detamore
Nov 1, 1984·Acta Oto-laryngologica·M AnnikoR Wróblewski

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