Calcium carbonate apatite deposition in the cervical spine with associated vertebral destruction. Case report

Journal of Neurosurgery
J G OjemannK B Baker

Abstract

This 52-year-old woman developed crystal deposition disease involving the cervical vertebrae. She presented with symptomatic spinal cord compression secondary to extensive calcified lesions in the posterior elements of the cervical spine. Surgical decompression with posterior fusion was performed. Histological examination showed hardened deposits of calcium carbonate involving the soft tissue, and dissolution of the vertebral bone trabeculae. There was no inflammatory response to these deposits. One year postoperatively the patient developed severe pulmonary disease associated with the collagen-vascular disorder, scleroderma (calcinosis, Raynaud's phenomenon, esophageal hypomotility, sclerodactyly, and telangiectasia [CREST] syndrome). Calcium carbonate deposition disease represents an unusual clinical entity that is possibly associated with scleroderma or other collagen-vascular diseases, and it is distinct from ligamentum flavum calcification, calcium pyrophosphate deposition disease, and hydroxyapatite deposition disease.

References

Feb 7, 1976·Lancet·P A DieppeD A Willoughby
Oct 1, 1977·Annals of Internal Medicine·H R SchumacherK Maurer
Sep 1, 1991·AJR. American Journal of Roentgenology·M E SchweitzerD Resnick
Jan 1, 1986·Spine·M F CosciaJ A Pitcock
May 1, 1984·Surgical Neurology·K NakajimaS Ishii
Apr 1, 1984·Arthritis and Rheumatism·D KuntzA Dryll
Nov 1, 1994·Radiographics : a Review Publication of the Radiological Society of North America, Inc·T L MundayW R Smoker
Jan 1, 1993·Skeletal Radiology·G OkadaH Yada
May 1, 1996·Skeletal Radiology·K OhashiM Takagi

❮ Previous
Next ❯

Citations

Jul 15, 1998·Arthritis and Rheumatism·D ParanD Caspi
May 23, 2006·Skeletal Radiology·M ZiadéA K-L So
Oct 6, 2006·European Radiology·Nathalie BoutryAnne Cotten
Apr 28, 2001·Joint, Bone, Spine : Revue Du Rhumatisme·P CabreS Arfi
Jun 22, 2005·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Lawrence P PanychRobert V Mulkern
Aug 29, 2020·Current Rheumatology Reports·Carrie RichardsonJohn Varga

❮ Previous
Next ❯

Methods Mentioned

BETA
electrophoresis
biopsy

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.