Calcium channel blockers and Alzheimer's disease

Neural Regeneration Research
Yi TanHong Qing

Abstract

Alzheimer's disease is characterized by two pathological hallmarks: amyloid plaques and neurofibrillary tangles. In addition, calcium homeostasis is disrupted in the course of human aging. Recent research shows that dense plaques can cause functional alteration of calcium signals in mice with Alzheimer's disease. Calcium channel blockers are effective therapeutics for treating Alzheimer's disease. This review provides an overview of the current research of calcium channel blockers involved in Alzheimer's disease therapy.

Citations

Jan 10, 2021·Journal of Molecular Neuroscience : MN·Olayemi Joseph OlajidePhilip Adeyemi Adeniyi
Apr 4, 2021·Journal of Clinical Medicine·Alexandru CojocaruEugen Osiac

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