Calcium deficiency alters chorda tympani nerve responses to oral calcium chloride

Physiology & Behavior
M Inoue, Michael G Tordoff

Abstract

As a preliminary examination of the influence of calcium deficiency on gustatory sensitivity to calcium, we recorded electrophysiological responses of the chorda tympani nerve of calcium-replete and calcium-deprived rats. Relative to rats fed calcium-replete diet, rats fed low calcium diet had lower electrophysiological response thresholds to CaCl2 (300 vs. 30 microM) and calcium lactate (300 vs. 100 microM) but not NaCl. The calcium-deprived animals had a greater chorda tympani response to 30, 100 and 300 microM CaCl2 and 30 and 100 microM calcium lactate but a smaller chorda tympani response to 30, 100 and 300 mM CaCl2 and to 100 mM MgCl2. A behavioral study using an ascending series of 48-h two-bottle preference tests showed that the threshold for acceptance of CaCl2 was similar to the electrophysiological threshold (310 microM in replete rats, 100 microM in calcium-deprived rats). These findings raise the possibility that changes in calcium status influence the perception of calcium, which, in turn, influences calcium intake.

References

Jan 1, 1978·The Japanese Journal of Physiology·Y Kitada
May 1, 1979·The Journal of General Physiology·R J Contreras, M Frank
Oct 1, 1992·Comparative Biochemistry and Physiology. Comparative Physiology·M S Herness
Aug 1, 1985·Behavioral Neuroscience·T Kosten, R J Contreras
Sep 1, 1989·Physiology & Behavior·L Millelire, B Woodside
Jan 1, 1986·Physiology & Behavior·F Ferrell, A Z Dreith
Oct 1, 1971·Physiology & Behavior·S S Schiffman, R P Erickson
Aug 1, 1971·Animal Behaviour·B O Hughes, D G Wood-Gush
Dec 1, 1965·Journal of Comparative and Physiological Psychology·J L Falk
Aug 1, 1967·Journal of Comparative and Physiological Psychology·W L Rodgers
Aug 1, 1980·The Journal of General Physiology·A M Hyman, M E Frank
Aug 1, 1980·The Journal of General Physiology·A M Hyman, M E Frank
Aug 1, 1996·Chemical Senses·M G Tordoff
Feb 15, 1963·The Japanese Journal of Physiology·S YAMASHITA

❮ Previous
Next ❯

Citations

Jul 3, 2008·Physiological Genomics·Michael G TordoffStuart McCaughey
Oct 1, 2008·Progress in Neurobiology·Marion E FrankRobert J Contreras
May 12, 2007·Physiology & Behavior·Michael G TordoffDanielle R Reed
Sep 18, 2013·Physiology & Behavior·Anna Voznesenskaya, Michael G Tordoff
Jan 11, 2012·Physiology & Behavior·Glen J GoldenMichael G Tordoff
Dec 6, 2008·Biochemical and Biophysical Research Communications·Ana San GabrielKunio Torii
Mar 6, 2009·Appetite·Michael G Tordoff, Mari A Sandell
Jul 10, 2012·Scientific Reports·Michael G TordoffPeihua Jiang
Oct 3, 2020·Animal Science Journal = Nihon Chikusan Gakkaihō·Mariana PederneraJuan J Villalba
Aug 12, 2000·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·T H Moran, J Schulkin
Oct 3, 2001·Physiological Reviews·M G Tordoff
Feb 26, 2016·The Biochemical Journal·Ryusuke Yoshida, Yuzo Ninomiya
Mar 14, 2021·Mammalian Genome : Official Journal of the International Mammalian Genome Society·Cailu LinDanielle R Reed

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Appetite
Stuart A McCaughey, Michael G Tordoff
Appetite
Stuart A McCaughey, Michael G Tordoff
Physiological Genomics
Michael G TordoffStuart A McCaughey
© 2021 Meta ULC. All rights reserved