Calcium-dependent association of glutathione S-transferase with the human erythrocyte membrane

Biochemical and Biophysical Research Communications
P H White, G A Plishker

Abstract

Elevations in intracellular calcium increase the adsorption of a cytoplasmic protein to human red blood cell membrane. This protein migrates on SDS polyacrylamide gels at 23,000 daltons and has been called band 8. The association of this protein with the membrane is increased in sickle cell anemia. This protein is extracted from the membrane with EGTA, a calcium chelator. Enzymatic and immunological studies identify band 8 as a glutathione S-transferase.

References

Apr 13, 1979·Biochemical and Biophysical Research Communications·R MorgensternL Ernster

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Citations

Jan 1, 1987·General Pharmacology·G Del BoccioC Di Ilio
Sep 1, 1990·Veterinary Pathology·M M ChristopherJ W Eaton
Oct 1, 1986·The American Journal of Physiology·G A PlishkerE D Cadman
Mar 17, 1997·Biochemical and Biophysical Research Communications·R B Moore, S K Shriver

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