Calcium-dependent potentials in mammalian red nucleus neurons in vitro

Neuroscience Research
M KubotaN Tsukahara

Abstract

Intracellular recordings were made from red nucleus (RN) neurons in guinea-pig slice preparations. The slow afterhyperpolarization (AHP) following an action potential was reversibly abolished by Co2+ or Mn2+. Its amplitude was dependent on the extracellular K+ concentration. When tetraethylammonium was added to the perfusing solution, a tetrodotoxin-resistant regenerative depolarization was evoked which was blocked by Co2+ or Mn2+. There results suggest that the slow AHP is produced by an increase in Ca2+-dependent K+ conductance and that RN neurons have a voltage-dependent Ca2+ conductance.

References

Jan 1, 1978·Annual Review of Biophysics and Bioengineering·R W Meech
Sep 1, 1979·Pflügers Archiv : European journal of physiology·W J LedererD A Eisner
Oct 21, 1977·Brain Research·P A Schwartzkroin, M Slawsky
Jan 1, 1984·Experimental Brain Research·H SakaguchiN Tsukahara
Jan 1, 1981·Annual Review of Neuroscience·S Hagiwara, L Byerly
Feb 1, 1983·The Journal of Physiology·Y Harada, T Takahashi

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Citations

Mar 8, 2002·Neuroscience·M C JiangUNKNOWN Department of Physiology, Institute for Neuroscience, Northwestern University Medical School, 303 E. Chicago Avenue, Chicago
Dec 2, 2011·Journal of Biomedicine & Biotechnology·Kaeffer Bertrand

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