PMID: 3213442Dec 1, 1988Paper

'Calcium fluoride-like' material formed in partially demineralized human enamel in vivo owing to the action of fluoridated toothpastes

Acta Odontologica Scandinavica
J ArendsT G Dijkman

Abstract

In this paper are presented the results of a chemical analysis of partially demineralized enamel lesions positioned under plaque in vivo for 3 weeks. During the experimental period the samples were brushed with fluoridated or non-fluoridated toothpaste systems. After the experiment the fluoride and protein uptake was determined. Furthermore, KOH extractions of the lesions were carried out and the solutions analyzed for calcium, fluoride, and phosphate. The results show that 'CaF2-like' material is most likely formed inside lesions during the in vivo period. This in indicated from chemical analysis, Raman spectroscopy, and SEM observations. The amount of CaF2-like material is on the order of 0.1 wt% if we consider its formation all over the enamel lesions, or 1 wt% if we assume its formation in interprismatic regions of the enamel only. About 40% of the fluoride taken up from toothpaste systems is in the form of CaF2-like material. In vivo there is a substantial influx of proteins (approximately 0.3%) and also a very large influx of phosphate ions. The effect of CaF2-like material is most likely strongly dependent on conditions in the lesion, such as pH change.

References

Jan 1, 1988·Caries Research·H De BruynJ Arends
Dec 1, 1983·Journal of Dental Research·D G NelsonJ Arends
Feb 1, 1982·Journal of Dental Research·S ChanderD W Fuerstenau

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Citations

Sep 15, 2009·Dental Materials : Official Publication of the Academy of Dental Materials·Toshiyuki SugeShigeyuki Ebisu
Apr 1, 2007·Journal of Applied Oral Science : Revista FOB·Fernanda de Carvalho Panzeri Pires-de-SouzaHeitor Panzeri
Nov 1, 1995·Advances in Dental Research·M Colbert
Apr 8, 2010·Clinical Oral Investigations·Stefano ChersoniCarlo Prati
Jun 1, 1994·Advances in Dental Research·O FejerskovV Baelum
Feb 1, 1990·Journal of Dental Research·B Ogaard
Feb 1, 1990·Journal of Dental Research·J Arends, J Christoffersen

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