PMID: 3745473Aug 1, 1986Paper

Calcium homeostasis in second trimester fetuses

Journal of Clinical Pathology
C MonizC H Rodeck

Abstract

The concentrations of ionised calcium ions (Ca++), total calcium, parathyroid hormone, pH, total protein, albumin, sodium, and potassium were measured in paired fetal and maternal blood from pregnancies at 15 to 24 weeks' gestation. Pure fetal blood samples were obtained fetoscopically. The concentrations of fetal ionised calcium ions (n = 26); mean (SD) 1.33 (0.12) mmol/l (5.32 (0.48) mg/100 ml) and those of parathyroid hormone (n = 9); 68 (19) pmol/l (58 (16) micrograms/100 ml) were significantly higher than those of the mothers: 1.18 (0.09) mmol/l (4.7 (0.4) mg/100 ml), and 40 pmol/l (less than 34 micrograms/100 ml), respectively. There was no difference between measured fetal and maternal total calcium, pH, and electrolytes. The fetal total protein and albumin concentrations increased with gestation but were always lower than the equivalent maternal values. The calculated total calcium was 0.23-0.45 mmol/l (0.9-1.8 mg/100 ml) higher in the fetal than in maternal blood from the same pregnancy. There were no fetal arteriovenous differences in ionised calcium ions despite higher venous pH.

References

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Citations

Mar 12, 2004·Seminars in Neonatology : SN·Stephanie C Hsu, Michael A Levine
Mar 1, 1992·American Journal of Obstetrics and Gynecology·K H NicolaidesC F Moniz
May 23, 2002·Medical Hypotheses·Donald R Taves
Jul 25, 2006·International Review of Cytology·Julie Lafond, Lucie Simoneau
Mar 23, 2017·Journal of Developmental Origins of Health and Disease·J K ClealL R Green
Nov 1, 1989·Baillière's Clinical Endocrinology and Metabolism·A D Care
Dec 31, 1997·Endocrine Reviews·C S Kovacs, H M Kronenberg
Aug 22, 2015·Journal of Radiological Protection : Official Journal of the Society for Radiological Protection·N B ShaginaM O Degteva
Sep 1, 1996·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·M L Ficinski, J H Mestman
Mar 1, 1991·Annals of Clinical Biochemistry·P D Mayne, I Z Kovar
May 1, 1997·Placenta·F J LinR S Tuan

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