Calcium orthophosphates (CaPO4 ): Occurrence and properties

Morphologie : Bulletin De L'Association Des Anatomistes
Sergey V Dorozhkin

Abstract

The present overview is intended to point the readers' attention to the important subject of calcium orthophosphates (CaPO4). This type of materials is of the special significance for the human beings because they represent the inorganic part of major normal (bones, teeth and antlers) and pathological (those appearing due to various diseases) calcified tissues of mammals. For example, atherosclerosis results in blood vessel blockage caused by a solid composite of cholesterol with CaPO4, while dental caries (tooth decay) and osteoporosis (a low bone mass with microarchitectural changes) mean a partial decalcification of teeth and bones, respectively, that results in replacement of a less soluble and harder biological apatite by more soluble and softer calcium hydrogenorthophosphates. Due to the compositional similarities to the calcified tissues of mammals, CaPO4 are widely used as biomaterials for bone grafting purposes. In addition, CaPO4 have many other applications. Thus, there is a great significance of CaPO4 for the humankind and, in this paper, an overview on the current knowledge on this subject is provided.

Citations

Aug 25, 2019·Nanomaterials·Ecaterina AndronescuBogdan Stefan Vasile
Nov 30, 2019·Brazilian Oral Research·Fabio Rocha BohnsFabricio Mezzomo Collares
Mar 12, 2021·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Mingxing RenSheng Yang
Aug 16, 2019·Micron : the International Research and Review Journal for Microscopy·Baptiste ArbezDaniel Chappard
Aug 25, 2018·Dental Materials : Official Publication of the Academy of Dental Materials·Roberto Ruggiero Braga

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