Calcium regulates independently ciliary beat and cell contraction in Paramecium cells

Cell Calcium
Yoshiaki Iwadate, Yasuo Nakaoka

Abstract

Intracellular Ca(2+) concentration is a well-known signal regulator for various physiological activities. In many cases, Ca(2+) simultaneously regulates individual functions in single cells. How can Ca(2+) regulate these functions independently? In Paramecium cells, the contractile cytoskeletal network and cilia are located close to each other near the cell surface. Cell body contraction, ciliary reversal, and rises in ciliary beat frequency are regulated by intracellular Ca(2+) concentration. However, they are not always triggered simultaneously. We injected caged calcium into Paramecium caudatum cells and continuously applied weak ultraviolet light to the cells to slowly increase intracellular Ca(2+) concentration. The cell bodies began to contract just after the start of ultraviolet light application, and the degree of contraction increased gradually thereafter. On the other hand, cilia began to reverse 1.4s after the start of ultraviolet application and reversed completely within 100ms. Ciliary beat frequency in the reverse direction was significantly higher than in the normal direction. These results indicate that cell body contraction is regulated by Ca(2+) in a dose-dependent manner in living P. caudatum. On the other ha...Continue Reading

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Citations

Sep 17, 2011·BMC Systems Biology·Nikolay V KotovNajl V Valeyev
Dec 1, 2015·Cytoskeleton·Naoki NarematsuYoshiaki Iwadate
May 31, 2011·Journal of Theoretical Biology·Shunsuke Ooyama, Tatsuo Shibata
Nov 30, 2012·The Journal of Eukaryotic Microbiology·Heidi K GrønlienOlav Sand
Jul 22, 2018·Proceedings of the National Academy of Sciences of the United States of America·Beatrice Freya Lucy EdwardsJack Daniel Sunter
Feb 27, 2021·Biochemical and Biophysical Research Communications·Audrey Dussutour

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