Calcium-requiring step in the uptake of deoxyribonucleic acid molecules through the surface of competent pneumococci.

Journal of Bacteriology
H Seto, A Tomasz

Abstract

The conversion of surface-adsorbed deoxyribonucleic acid (DNA) molecules to a state in which they are inaccessible to exogenous deoxyribonuclease requires specifically calcium ions; magnesium ions cannot replace calcium ions. Virtually maximal levels of nuclease-resistant DNA binding and genetic transformation can be obtained in media free from magnesium and containing only calcium ions. It is suggested that the calcium-requiring process is the transport of DNA molecules across the plasma membrane. Magnesium ions stimulate both the loss of surface-adsorbed DNA to the medium and the extracellular degradation of DNA.

References

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Citations

Jan 1, 1997·Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease·S A Lacks
May 8, 2015·Environmental Microbiology Reports·Mirian DomenechErnesto García
Jan 26, 2000·Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease·M C Trombe
Aug 11, 2001·Critical Reviews in Oral Biology and Medicine : an Official Publication of the American Association of Oral Biologists·D G Cvitkovitch
Apr 1, 1981·Journal of Bacteriology·W J Page, J L Doran
Apr 1, 1981·Journal of Bacteriology·R Gromkova, S Goodgal

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