PMID: 18406777Dec 1, 1996Paper

Calcium signaling and secretion in pituitary cells

Trends in Endocrinology and Metabolism : TEM
R Zorec

Abstract

An important trigger of hormone secretion from pituitary cells is a rise in cytosolic Ca(2+) ([Ca(2+)](i)). Pituitary cells may modulate [Ca(2+)](i) by an increased membrane flux from the extracellular space and/or by a release from intracellular stores. Both mechanisms can support exocytosis, although in different pituitary cell types one or the other mechanism may predominate. Molecular events transducing a rise in [Ca(2+)](i) into hormone secretion are still poorly understood. Here, the exocytotic machinery in pituitary cells is briefly reviewed in terms of the spatial organization of [Ca(2+)](i) elevation relative to the Ca(2+) sensor(s).

References

May 1, 1992·Endocrine Reviews·S S Stojilković, K J Catt
Oct 1, 1988·Trends in Neurosciences·S J Smith, G J Augustine
Sep 1, 1988·Proceedings of the National Academy of Sciences of the United States of America·G A ShangoldR J Miller
Oct 1, 1986·Physiological Reviews·S Ozawa, O Sand
Nov 1, 1982·Proceedings of the National Academy of Sciences of the United States of America·E Neher, A Marty
Nov 1, 1993·Trends in Neurosciences·J M Trifaró, M L Vitale
Aug 1, 1994·Trends in Neurosciences·T Söllner, J E Rothman
Jul 1, 1995·The Journal of Membrane Biology·L ChernomordikJ Zimmerberg
Apr 1, 1995·Trends in Neurosciences·R D Burgoyne, A Morgan
Dec 20, 1994·Proceedings of the National Academy of Sciences of the United States of America·R H ChowE Neher
Apr 1, 1994·Neuron·J R Monck, J M Fernandez
Oct 6, 1994·Nature·R HeidelbergerG Matthews
Oct 1, 1993·Pflügers Archiv : European journal of physiology·L Kocmur, R Zorec
Oct 1, 1995·Kidney International·E Perez-Reyes, T Schneider
Nov 1, 1995·Pflügers Archiv : European journal of physiology·M Rupnik, R Zorec
Mar 15, 1996·Science·P De CamilliP Novick
Sep 1, 1995·Trends in Cell Biology·A Morgan, R D Burgoyne
Dec 1, 1996·Trends in Endocrinology and Metabolism : TEM·P Mollard, W Schlegel

❮ Previous
Next ❯

Citations

Apr 30, 1999·Molecular and Cellular Endocrinology·C K BauerJ R Schwarz
Dec 1, 1996·Trends in Endocrinology and Metabolism : TEM·P Mollard, W Schlegel
Dec 1, 1996·Trends in Endocrinology and Metabolism : TEM·S S Stojilkovic
Sep 13, 2005·Annals of the New York Academy of Sciences·Simon SedejRobert Zorec
Jun 2, 2005·Domestic Animal Endocrinology·D A ZiebaG L Williams
Oct 7, 2005·American Journal of Physiology. Cell Physiology·Maja PotokarRobert Zorec
Jul 24, 2010·Endocrine Reviews·Stanko S StojilkovicRichard Bertram

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.