Calcium solubilization and retention in the gastrointestinal tract in chicks (Gallus domesticus) as a function of gastric acid secretion inhibition and of calcium carbonate particle size

The British Journal of Nutrition
F GuinotteA Soumarmon

Abstract

In chicks, immature pullets and laying hens, the inhibition of gastric acid secretion by omeprazole, an H+,K(+)-transporting ATPase (EC 3.6.1.36) inhibitor, greatly increased proventricular and gizzard pH values. Consequently, gizzard soluble Ca concentration deceased and the insoluble Ca fraction increased. Inhibition of acid secretion increased duodenal pH values in immature pullets and laying hens but not in chicks. Duodenal soluble and ionic Ca concentrations were lowered by gastric acid inhibition in chicks and to a larger extent in immature pullets and laying hens. The use of Ca of coarse particle size increased the gizzard insoluble Ca fraction in chicks and pullets. However, it did not influence its soluble Ca fraction in chicks but tended to reinforce the negative effect of omeprazole on soluble Ca in the gizzard and duodenum of chicks and laying hens. Coarse particles of Ca led to an increase in gizzard and duodenal soluble Ca at the end of eggshell calcification in laying hens. An enhancement in the level of Ca in the diet from 10 to 36 g/kg increased gizzard soluble Ca and duodenal soluble and ionic Ca concentrations in immature and adult hens. Intestinal Ca retention and bone mineralization was unaffected by gastri...Continue Reading

References

Sep 1, 1976·British Poultry Science·P Mongin
Feb 1, 1986·Calcified Tissue International·J Tuukkanen, H K Väänänen
Aug 1, 1988·Calcified Tissue International·C Y Pak, L V Avioli
Sep 1, 1986·European Journal of Cancer & Clinical Oncology·Y KikuchiK Kato
Jul 11, 1985·The New England Journal of Medicine·R R Recker
Jun 1, 1967·The American Journal of Physiology·J F Long
May 1, 1967·Annals of Internal Medicine·P IvanovichC Rich
Jul 2, 1983·British Medical Journal·R P WaltR E Pounder
Mar 1, 1984·The Journal of Clinical Investigation·G W Bo-LinnJ S Fordtran
Jan 1, 1990·Nutrition Research Reviews·A G Low

Citations

Jul 3, 2008·Digestion·D PohlKandahar Study Group
Feb 13, 2018·British Poultry Science·S A LeeM R Bedford
Mar 6, 2018·Poultry Science·P E Eusebio-BalcazarM M Beck
Mar 7, 2019·Poultry Science·Eugenia HerwigHenry L Classen
Jun 12, 1999·Pathology International·M SasakiY Nakanuma
Aug 17, 2004·World Journal of Urology·Björn WulltWiking Mansson
Sep 8, 2011·Journal of the American College of Nutrition·Ann E ElbleConnie M Weaver
Nov 5, 2020·Avian Pathology : Journal of the W.V.P.A·Van Limbergen TommyRichard Ducatelle

Related Concepts

Metazoa
Chalk
Calcium, Dietary
Duodenum
Egg Shell
Gastric Acid
Hydrogen-Ion Concentration
Intestinal Absorption
Omeprazole magnesium
Particle Size

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Alzheimer's Disease: MS4A

Variants within the membrane-spanning 4-domains subfamily A (MS4A) gene cluster have recently been implicated in Alzheimer's disease in genome-wide association studies. Here is the latest research on Alzheimer's disease and MS4A.

Pediculosis pubis

Pediculosis pubis is a disease caused by a parasitic insect known as Pthirus pubis, which infests human pubic hair, as well as other areas with hair including eye lashes. Here is the latest research.

Rh Isoimmunization

Rh isoimmunization is a potentially preventable condition that occasionally is associated with significant perinatal morbidity or mortality. Discover the latest research on Rh Isoimmunization here.

Genetic Screens in iPSC-derived Brain Cells

Genetic screening is a critical tool that can be employed to define and understand gene function and interaction. This feed focuses on genetic screens conducted using induced pluripotent stem cell (iPSC)-derived brain cells. It also follows CRISPR-Cas9 approaches to generating genetic mutants as a means of understanding the effect of genetics on phenotype.

Enzyme Evolution

This feed focuses on molecular models of enzyme evolution and new approaches (such as adaptive laboratory evolution) to metabolic engineering of microorganisms. Here is the latest research.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Pharmacology of Proteinopathies

This feed focuses on the pharmacology of proteinopathies - diseases in which proteins abnormally aggregate (i.e. Alzheimer’s, Parkinson’s, etc.). Discover the latest research in this field with this feed.

Alignment-free Sequence Analysis Tools

Alignment-free sequence analyses have been applied to problems ranging from whole-genome phylogeny to the classification of protein families, identification of horizontally transferred genes, and detection of recombined sequences. Here is the latest research.