PMID: 3759251Jan 1, 1986Paper

Calculated initial chemotherapy in mechanically-ventilated postoperative patients with peritonitis, sepsis and pneumonia

Infection
G HünefeldH Bunzendahl

Abstract

Calculated chemotherapy is based on the knowledge of the typical bacterial agents of a particular infection. From January 1983 to August 1985 bacteriological findings from surgical patients with peritonitis, septicemia or pneumonia treated in an intensive care unit were analysed. The study concentrated on those findings only which differed from previous bacteriological investigations. During the first three days 53 patients on assisted ventilation suffering from peritonitis exhibited mainly enterobacteria in their peritoneal secretions. At day 10 or later we also found bacteria from the pseudomonas group. At that time the bacterial spectrum of bronchial secretions was comparable to that of the peritoneal secretions of the same patient. After day 10, the bacterial spectrum was similar in 36 ventilated patients without peritonitis, in 56 patients suffering from post-operative pneumonia and in peritonitis patients. According to our findings, calculated chemotherapy may be based on the fact that patients with peritonitis who cannot be cured within a few days have a bacterial flora comparable to that of patients with septicemia or pneumonia. Patients with severe infections following surgery, such as potentially fatal pneumonia, gene...Continue Reading

References

Jan 1, 1986·Langenbecks Archiv für Chirurgie·G HünefeldR Pichlmayr
Mar 1, 1985·Diagnostic Microbiology and Infectious Disease·A L BarryR Kundargi
Dec 1, 1983·The Journal of Antimicrobial Chemotherapy·F M KahanJ Birnbaum
Dec 1, 1983·Antimicrobial Agents and Chemotherapy·L J EronD M Poretz
Dec 1, 1983·The Journal of Antimicrobial Chemotherapy·G B CalandraK R Brown
Oct 1, 1984·European Journal of Clinical Microbiology·G L DrusanoS C Schimpff
Oct 1, 1984·European Journal of Clinical Microbiology·C E NordG Stiernstedt
Aug 1, 1983·Antimicrobial Agents and Chemotherapy·D A StrandbergD J Drutz
Jun 1, 1982·European Journal of Clinical Microbiology·P C AppelbaumG A Pankuch

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